Case report : Anterior Open bite after injection of Botulinum Toxin on Masseter Muscles

보툴리눔 톡신 교근 주입 후 발생한 전방 개교합 증례보고

  • Ryu, Ji-won (Department of Oral Medicine, School of Dentistry, Chosun University)
  • 유지원 (조선대학교 치의학전문대학원 구강내과학교실)
  • Received : 2013.10.08
  • Accepted : 2013.10.29
  • Published : 2013.12.30


Botulinum neurotoxin(BoNT) is a protease exotoxin produced from Clostridium botulinum. It works by blocking the release of acetylcholine from cholinergic nerve endings causing inactivity of muscles or glands. Recently, the therapeutic use of BoNT have expanded to include a wide range of medical and dental conditions. Botulinum neurotoxin type A(BoNT/A) is used off-label in the orofacial region to treat primary and secondary masticatory and facial muscle spasm, severe bruxism, facial tics, orofacial dyskinesias, dystonias, and hypertrophy of the masticatory muscles. Local hematoma, infection, and persistent pain in the injection site are the site-of-injection side effects. Medication-related side effects are adjacent muscle weakness, slurred speech, an alteration in the character of the saliva, and severe headaches. In most cases, these complications are not persistent and bothersome. We reported a case report of a patient who had transient anterior open bite after BoNT/A injection on masseter muscles to treat the refractory myofascial pain.


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