Establishment of Optimal Fermentation Conditions for Steam-dried Ginseng Berry via Friendly Bacteria and Its Antioxidant Activities

생체친화성 균주에 의한 인삼열매증포 추출물의 최적발효조건 및 항산화활성

  • Kim, Seung Tae (Department of Marine Molecular Biotechnology, College of Life Science, Gangneung-Wonju National University) ;
  • Kim, Hee Jung (Department of Marine Molecular Biotechnology, College of Life Science, Gangneung-Wonju National University) ;
  • Jang, Su Kil (Department of Marine Molecular Biotechnology, College of Life Science, Gangneung-Wonju National University) ;
  • Lee, Do Ik (Department of Immunology, College of Pharmacy, Chung-Ang University) ;
  • Joo, Seong Soo (Department of Marine Molecular Biotechnology, College of Life Science, Gangneung-Wonju National University)
  • 김승태 (강릉원주대학교 생명과학대학 생물의약신소재연구실) ;
  • 김희정 (강릉원주대학교 생명과학대학 생물의약신소재연구실) ;
  • 장수길 (강릉원주대학교 생명과학대학 생물의약신소재연구실) ;
  • 이도익 (중앙대학교 약학대학 면역질환연구실) ;
  • 주성수 (강릉원주대학교 생명과학대학 생물의약신소재연구실)
  • Received : 2012.10.16
  • Accepted : 2013.01.16
  • Published : 2013.02.28


In this study, we observed optimal conditions and suitable bacteria for the fermentation of steam-dried ginseng berry extracts (SGB) and determined antioxidant effects of the fermented extracts. Five bacteria (Lactobacillus fermentarum, L. plantarum, L. brevis, L. casei, Bacillus subtillis) were examined on their growth activities and viabilities in various culture temperatures ($25-35^{\circ}C$) and concentrations (25-100%). L. plantarum was considered to be the most suitable bacteria for the fermentation in both growth activity and viability. Moreover, the extracts fermented with L. plantarum showed more potent antioxidant efficacy in both 1,1-diphenyl-2-picrylhydrazyl radical and hydroxyl radical scavenging assay. High performance liquid chromatography analysis revealed that fermentation with L. plantarum changed the contents and components of ginsenosides. In conclusion, these data suggest that L. plantarum efficiently ferment SGB and the fermented extracts may have therapeutical values against oxidative stress and be a good candidate in adjuvant therapy where ginsenoside would be the main composition.


Supported by : 보건복지부


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