The Influence of Botulinum Toxin Type A Masticatory Efficiency

보툴리눔 A형 독소가 저작효율에 미치는 영향

  • Park, Hyung-Uk (Department of Orofacial Pain & Oral Medicine, Yonsei Dental Hospital, Yonsei University Colledge of Dentistry) ;
  • Kwon, Jeong-Seung (Department of Orofacial Pain & Oral Medicine, Yonsei Dental Hospital, Yonsei University Colledge of Dentistry) ;
  • Kim, Seong Taek (Department of Orofacial Pain & Oral Medicine, Yonsei Dental Hospital, Yonsei University Colledge of Dentistry) ;
  • Choi, Jong-Hoon (Department of Orofacial Pain & Oral Medicine, Yonsei Dental Hospital, Yonsei University Colledge of Dentistry) ;
  • Ahn, Hyung-Joon (Department of Orofacial Pain & Oral Medicine, Yonsei Dental Hospital, Yonsei University Colledge of Dentistry)
  • 박형욱 (연세대학교 치과대학 구강내과학교실) ;
  • 권정승 (연세대학교 치과대학 구강내과학교실) ;
  • 김성택 (연세대학교 치과대학 구강내과학교실) ;
  • 최종훈 (연세대학교 치과대학 구강내과학교실) ;
  • 안형준 (연세대학교 치과대학 구강내과학교실)
  • Received : 2013.02.12
  • Accepted : 2013.03.04
  • Published : 2013.03.30


This study was aimed to evaluate the masticatory efficiency after botulinum toxin type A (BTX-A) injection during 12 weeks using objective and subjective test. Also, we compared the difference of masticatory efficiency between group that injected into the masseter muscle only (M-group) and group that injected into the masseter and temporalis muscle (M-T group). The mixing ability index (MAI) was used as the objective indicator, and visual analogue scale (VAS) and food intake ability (FIA) index were used as the subjective indicators. It was concluded that masticatory efficiency was significantly lowered after a BTX-A injection into the masticatory muscle, but it gradually recovered in a predictable pattern by the 12 weeks. The disturbance of subjective masticatory efficiency was lasted longer than objective masticatory efficiency. The masticatory efficiency was lower in M-T group than M group. It was statistically significant in the VAS and FIA at 4 weeks, but the MAI showed no significancy. After 4weeks, there was rapid recovery of muscle function in M-T group, and the difference between two groups was not significant. It could be concluded that there will be no serious disturbance of mastication compared to injection is done only into the masseter muscle, even if injection is done into the masseter and temporalis muscle in dose of this study. According to the food properties, it was confirmed that people feel more discomfort on taking hard and tough foods after BTX-A injection and not only hard foods, but also intake of soft and runny foods were influenced by botulinum toxin injection.


Supported by : Yonsei Uneiversity Colledge of Dentistry


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