DOI QR코드

DOI QR Code

A Clinical Study for Effect of Herbal Cosmetics Containing Cortex Betulae Platyphyllae Extract Complex on Acne

화피추출물 복합제 화장품의 여드름에 대한 임상적 연구

  • Park, Soo-Yeon (Department of Opthalmology & Otolaryngology & Dermatology, Collage of Oriental medicine, Dong-Shin University) ;
  • Na, Chang-Soo (Department of Meridian & Acupoint, Collage of Oriental Medicine, Dong-shin University) ;
  • Jeong, Won-Cheol (Mediplan Co., Ltd.) ;
  • Lee, Jong-Cheol (Department of Opthalmology & Otolaryngology & Dermatology, Collage of Oriental medicine, Dong-Shin University)
  • 박수연 (동신대학교 한의과대학 한방안이비인후피부과학교실) ;
  • 나창수 (동신대학교 한의과대학 경혈학 교실) ;
  • 정원철 (주)메디플랜) ;
  • 이종철 (동신대학교 한의과대학 한방안이비인후피부과학교실)
  • Received : 2013.07.09
  • Accepted : 2013.08.08
  • Published : 2013.08.25

Abstract

Objective : The primary purpose of present study is to evaluate the effect of herbal cosmetics containing Cortex Betulae Platyphyllae extract complex on acne. The second is to comparatively evaluate safety of this cosmetics. Methods : We opened collecting of applicant that men and women(the 18~35-year-old) with acne on face. We selected subjects who came up to entire inclusion criteria and were not included in the exclusion criteria. We checked changes of Acne Global score, skin sebum, moisture, pores counts, Skindex-29 for 8 weeks. Results : 1. Comparison of changes in Global score, it declined in both experimental group and control group. But Experimental group showed a statistically significant decline than control group. 2. Comparison of changes in sebum and moisture, it declined in both experimental group and control group. But there was no statistically significant difference between those two groups. 3. Comparison of changes in erythema normal area, it declined in both experimental group and control group. But there was no statistically significant difference between those two groups. 4. Comparison of changes in pore counts, it increased statistically significantly in both experimental group and control group. 5. Comparison of changes in Skindex-29, it declined in both experimental group and control group. But there was no statistically significant difference between those two groups. Conclusion : Considering the above experiments, it is suggested that herbal cosmetics containing Cortex Betulae Platyphyllae extract complex have a positive effect on acne.

Keywords

Acknowledgement

Supported by : 보건복지부

References

  1. Korean Dermatological Association Textbook Compilation Committee. 5th Edition Dermatology. Seoul:Ryo Moon Gak. 2008:446-54.
  2. Jeong JY. Acne. Seoul:MD world. 2007:15, 32-5, 63-5, 142-58, 207-8, 210-2, 214, 517-38, 711-2, 812-25.
  3. Jeong JY, Ha CM. Primary care of skin disease revision vol. 1. Chungbuk:MD world. 2006:391-8.
  4. Kim BJ, Lee SJ. Aesthetic dermatology. Seoul:Ryo Moon Gak. 2009:115-37.
  5. Chae BY. The Clinical Study of Acne Patients. The Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology. 1998;11(1):253.
  6. Lee SH, An BG. The Quality of Life of Acne Patients. Korean Journal of Dermatology. 2003;41(10):1274-5.
  7. Yoshiki M, Masahiro T, Fukumi F. The Latest Acne Treatment Techniques. Seoul: Koon Ja Publishing, Inc. 2009:220.
  8. Baek SC, Jo EH, Mendgerel, Park MC. Effect of Sophorae Radix-Skin Lotion on Acne. The Journal of Korean Oriental Medical Ophthalmology & Orolaryngology & Dermatology. 2011;24(1):111-20.
  9. Hyoung YG. The study on the effect of Okyongsan in Acnes. Graduate School of Woo Suk University Master's thesis. 1998.
  10. Kim MS, Kim JH, Chae BY. The Effects of Chungsangbangpoongtang Extact Solution by Oral Administration and Topical Application on Acne. Kyung Hee Medical. 1992;8(3): 265-75.
  11. Im HS. The Experimental Study of Gagambipachungpe-Eum on Acne. Graduate School of Kyung Hee University Master's thesis. 2000.
  12. Rho SW. The Experimental Study on the Effects of Gamidangguijakyaktang Extact Solution Applicatable to the Treatment of Acne. Graduate School of Kyung Hee University Master's thesis. 2000.
  13. Yang SJ. Effects of Hedyotis diffusa in patients with acne. Graduate School of Complementary Alternative Medicine Pochon CHA University Master's thesis. 2005.
  14. Kim SB, Kim KJ. Effect of the addition temperament drugs of Yeongyopaedock-san on acne in the state of inflammation. The Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology. 2002;15(1):50-62.
  15. Seo HS. Studies on the Effects of Gami-Shengmayuipung-tang on Acnes. The Journal of Korean Oriental Medical Society. 2005;26(1):134-47.
  16. Yoo JG, Seo HS. The Effects of Yeouigeumhwang-san on Anti-Inflammation and Anti-Propionibacterium acnes. The Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology. 2007;20(2):77-88.
  17. Choi KH, Seo HS. The Effects of Jeondo-san on Anti-Inflammation and Anti-Propionibacterium acnes. The Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology. 2007;20(2): 89-101.
  18. Jung SY. The Effects of Samhwangseje on Anti-Inflammation, Antioxidant And Anti-Propionibacterium acnes. Graduate School of Sangji University Doctoral thesis. 2009.
  19. Chae YM. Jungyakyakmyeongsajun. Beijing: Chinese Medicine Publisher. 1996:44.
  20. Sin MG, Jeong BY. Dohae Hyangyakdaesajeon. Seoul:Yeongrimsa. 380-1, 735, 803-4.
  21. Sin MG. Clinical Traditional Herbalogy. Seoul:Yeongrimsa. 2002:399-400, 844.
  22. Chinese Medicine University Association Textbook Compilation Committee. Herbalogy. Seoul:Yeongrimsa. 2004:681-2, 741.
  23. Park SY, Na CS, Jeong WC, Lee JC. A Literature Study of Pericarpium Granati and Cortex Betulae Platyphyllae. The Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology. 2012;25(3): 13-33. https://doi.org/10.6114/jkood.2012.25.3.013
  24. Kim WI, Kim JE, Lee SH, Moon YS, Lee SH, Park SY, Na CS. Antioxidative and Antimicrobial Activities of Water- and Ethanol-Extracts from Betula platyphylla var. japonica, Punica granatum and Rhus javanica. Kor. J. Herbology. 2013;28(3):45-51. https://doi.org/10.6116/kjh.2013.28.3.45
  25. Department of Dermatology, Seoul National University College of Medicine. Dermatology for medical students. Seoul:Korea Medical Book Publishing. 2006:229-33.
  26. Ahn SG, Seong YO, Song JW. Acne Bible. Seoul:Chinsol. 2006:61-83,94-159,244-54,263-9,272-80,283-96,302-38,348-79,384-94.
  27. Wang Q. Huangdi's Internal Classic Plain Questions Revisions. Seoul:Seongbosa. 1983:14.
  28. Lou Y. Yi Xue Gang Mu. Beijing:Zhong Yi Gu Ji Publishing. Inc. 1999:506.
  29. Wang K. Standards of Pattern Identification and Treatment. Taipei:Xin Wen Feng Chu Ban Gu Fen You Xian Gong Si. 1979:4,198.
  30. Heo J. Treasured Mirror of Eastern Medicine. Seoul:Beobin Munhwasa. 1999:511,515-20.
  31. Chen G, Yang S. Practical Diagnostics and Therapeutics of Integrated Traditional Chinese and Western Medicine. Beijing:China Medical Science and Technology Publishing. 1998:1496-8.
  32. Wang H. Peaceful holy Benevolent Prescriptions. Seoul:Seongbosa. 1979:1207, 1212, 1214-5, 1217.
  33. Cheng G. Medical Insights. Beijing:Zhong Yi Gu Ji Publishing Inc. 1999:146.
  34. Gu B. Practical Surgery of TCM. Shanghai:Shanghai Ke Xue Ji Zhu Publishing. Inc. 1985:535-6.
  35. Joo HA, Bae HJ, Hwang CY. A Literature Study about Comparion of Eastern-Western Medicine on the Acne. The Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology. 2012;25(2): 1-19.

Cited by

  1. The Review of Clinical Studies Published in The Journal of Korean Medical Ophthalmology & Otolaryngology & Dermatology vol.27, pp.4, 2014, https://doi.org/10.6114/jkood.2014.27.4.001
  2. 한방안이비인후피부과학회지에 게재된 여드름과 관련된 논문에 관한 고찰 vol.27, pp.3, 2014, https://doi.org/10.6114/jkood.2014.27.3.026
  3. 여드름의 변증 유형별 주요 증후에 관한 연구 vol.27, pp.4, 2014, https://doi.org/10.6114/jkood.2014.27.4.076
  4. 한약과 압출 치료에 병행한 황련해독탕 약침의 여드름 치료 22례 임상 보고 vol.28, pp.3, 2013, https://doi.org/10.6114/jkood.2015.28.3.114
  5. External Application of Herbal Medicines for Acne Vulgaris: A Systematic Review and Meta Analysis vol.23, pp.1, 2020, https://doi.org/10.3831/kpi.2020.23.002