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Flurbiprofen toxicity in 2 dogs

두 마리 개에서의 flurbiprofen 중독 2례

  • Lee, Ye-Hyun (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Nam, Eui-Hwa (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Park, Seol-Hee (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Song, Chi-Youn (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Lee, Yong-Uk (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Lee, Jong-Myung (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Park, Jung-Hoon (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Hwang, Cheol-Yong (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)
  • 이예현 (서울대학교 수의과대학) ;
  • 남의화 (서울대학교 수의과대학) ;
  • 박설희 (서울대학교 수의과대학) ;
  • 송치윤 (서울대학교 수의과대학) ;
  • 이용욱 (서울대학교 수의과대학) ;
  • 이종명 (서울대학교 수의과대학) ;
  • 박정훈 (서울대학교 수의과대학) ;
  • 황철용 (서울대학교 수의과대학)
  • Received : 2013.03.05
  • Accepted : 2013.06.17
  • Published : 2013.09.30

Abstract

Two dogs were presented with melena, vomiting and depression after accidental swallowing of candy form of Strepsils (flurbiprofen), which is one of non-steroidal anti-inflammatory drugs used in human medicine for controlling a sore throat. These dogs had common signs of anemia induced by gastrointestinal ulceration and hemorrhage with azotemia and leukocytosis. The dogs were treated with blood transfusion, fluid therapy, proton-pump inhibitor, antiemetics, mucus protectant and antibiotic. Although most of clinical signs of two dogs were resolved, azotemic problem with evidence of renal injury have remained.

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