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Effect of medicinal plant extract for hangover relief

약용식물 추출물의 숙취 해소 효과에 관한 연구

  • Hyun, Chang-Su (College of Veterinary Medicine, Jeju National University) ;
  • Park, Garyoung (College of Veterinary Medicine, Jeju National University) ;
  • Oh, Young Mi (College of Veterinary Medicine, Jeju National University) ;
  • Lee, Youngjae (College of Veterinary Medicine, Jeju National University) ;
  • Han, Chang-Hoon (College of Veterinary Medicine, Jeju National University)
  • 현창수 (제주대학교 수의과대학 수의학과) ;
  • 박가령 (제주대학교 수의과대학 수의학과) ;
  • 오영미 (제주대학교 수의과대학 수의학과) ;
  • 이영재 (제주대학교 수의과대학 수의학과) ;
  • 한창훈 (제주대학교 수의과대학 수의학과)
  • Received : 2014.08.08
  • Accepted : 2014.11.10
  • Published : 2014.12.31

Abstract

The present study was performed to evaluate the effect of medicinal plant extract on relieving hangovers in mice administered alcohol. The animals were divided into three groups. Each group was treated with fermented plant extract, non-fermented plant extract, or water 30 min after consuming ethanol (2 mL/kg). A locomotor activity test showed that all groups had decreased motor activity until 40 min after plant extract administration. The mice treated with water had lower motor activity until 100 min post-administration. However, the group treated with non-fermented plant extract showed increased motor activity 40 min post-administration, and the higher activity level was maintained until 120 min post-administration. The animals treated with fermented plant extract had a level of motor activity between those of the groups treated with water or non-fermented plant extract. Blood was collected from each mouse 120 min post-administration and aldehyde concentration was measured. The group treated with non-fermented plant extract had a significantly higher (p < 0.05) aldehyde concentration than the other groups. These results demonstrate that the non-fermented medicinal plant extract helped alleviate hangovers 40 min after administration by reducing aldehyde concentrations in the blood.

Acknowledgement

Supported by : 제주대학교

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