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Fatal cryptosporidiosis in a calf

송아지에서 발생한 중증 크립토스포리듐 증 증례

  • Baek, Kang-Hyun (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Hyun-Kyoung (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Kyung-Hyun (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Kim, Ha-Young (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Park, Jung-Won (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Bo-Ram (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Her, Ji-Woong (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Myoung-Heon (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Bae, You-Chan (Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency)
  • 백강현 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 이현경 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 이경현 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 김하영 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 박중원 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 이보람 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 허지웅 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 이명헌 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 배유찬 (농림축산검역본부 동물질병관리부 질병진단과)
  • Received : 2014.08.19
  • Accepted : 2014.11.26
  • Published : 2014.12.31

Abstract

A calf suffering from diarrhea was admitted to the Animal and Plant Quarantine Agency for diagnostic evaluation. Postmortem examination revealed that the mesenteric lymph node was enlarged and small intestine wall was thin. Microscopically, a large number of small round organisms were attached to the small intestine villi. Villous atrophy and proprial neutrophil infiltration were also observed. Based on modified Ziehl-Neelsen staining, electron microscopy, and ELISA results, the calf was diagnosed with fatal cryptosporidiosis.

Acknowledgement

Supported by : 농림축산검역본부

References

  1. Almawly J, Prattley D, French NP, Lopez-Villalobos N, Hedgespeth B, Grinberg A. Utility of halofuginone lactate for the prevention of natural cryptosporidiosis of calves, in the presence of co-infection with rotavirus and Salmonella Typhimurium. Vet Parasitol 2013, 197, 59-67. https://doi.org/10.1016/j.vetpar.2013.04.029
  2. Bjorkman C, Svensson C, Christensson B, de Verdier K. Cryptosporidium parvum and Giardia intestinalis in calf diarrhoea in Sweden. Acta Vet Scand 2003, 44, 145-152. https://doi.org/10.1186/1751-0147-44-145
  3. Bouzid M, Hunter PR, Chalmers RM, Tyler KM. Cryptosporidium pathogenicity and virulence. Clin Microbiol Rev 2013, 26, 115-134. https://doi.org/10.1128/CMR.00076-12
  4. Chai JY, Lee SH, Guk SM, Lee SH. An epidemiological survey of Cryptosporidium parvum infection in randomly selected inhabitants of Seoul and Chollanam-do. Korean J Parasitol 1996, 34, 113-119. https://doi.org/10.3347/kjp.1996.34.2.113
  5. Cheun HI, Cho SH, Lee JH, Lim YY, Jeon JH, Yu JR, Kim TS, Lee WJ, Cho SH, Lee DY, Park MS, Jeong HS, Chen DS, Ji YM, Kwon MH. Infection status of hospitalized diarrheal patients with gastrointestinal protozoa, bacteria, and viruses in the Republic of Korea. Korean J Parasitol 2010, 48, 113-120. https://doi.org/10.3347/kjp.2010.48.2.113
  6. Cho YI, Yoon KJ. An overview of calf diarrhea - infectious etiology, diagnosis, and intervention. J Vet Sci 2014, 15, 1-17. https://doi.org/10.4142/jvs.2014.15.1.1
  7. Naciri M, Lefay MP, Mancassola R, Poirier P, Chermette R. Role of Cryptosporidium parvum as a pathogen in neonatal diarrhoea complex in suckling and diary calves in France. Vet Parasitol 1999, 85, 245-257. https://doi.org/10.1016/S0304-4017(99)00111-9
  8. Deng M, Rutherford MS, Abrahamsen MS. Host intestinal epithelial response to Cryptosporidium parvum. Adv Drug Deliv Rev 2004, 56, 869-884. https://doi.org/10.1016/j.addr.2003.10.034
  9. Kuhnert-Paul Y, Bangoura B, Dittmar K, Daugschies A, Schmaschke R. Cryptosporidiosis: comparison of three diagnostic methods and effects of storage temperature on detectability of cryptosporidia in cattle faeces. Parasitol Res 2012, 111, 165-171. https://doi.org/10.1007/s00436-011-2813-6
  10. Moon S, Kwak W, Lee S, Kim W, Oh J, Youn S. Epidemiological characteristics of the first water-bone outbreak of cryptosporidiosis in Seoul, Korea. J Korean Med Sci 2013, 28, 983-989. https://doi.org/10.3346/jkms.2013.28.7.983
  11. Olson ME, O'Handley RM, Ralston BJ, McAllister TA, Thompson RCA. Update on cryptosporidium and giardia infections in cattle. Trends Parasitol 2004, 20, 185-191. https://doi.org/10.1016/j.pt.2004.01.015
  12. Panciera RJ, Thomassen RW, Garner FM. Cryptosporidial infection in a calf. Vet Pathol 1971, 8, 479-484. https://doi.org/10.1177/0300985871008005-00610
  13. Rhee JK, Seu YS, Park BK. Isolation and identification of Cryptosporidium from various animals in Korea. I. Prevalence of Cryptospordium in various animals. Kisaengchunghak Chapci 1991, 29, 139-148.
  14. Wee SH, Joo HD, Lee CG, Kim JT, Kang YB. Immunotherapy in calves experimentally infected with Cryptosporidium parvum. Korean J Vet Res 1998, 38, 366-370.
  15. Yang HJ, Kim CS. Prevalence of Cryptosporidium sp among calves and pigs in Jeonbuk province. Korean J Vet Serv 2001, 24, 133-138.