Effect of Antimicrobial Activity of the Glutaraldehyde Cross-linked Glucosamine

글루코사민-글루타르알데히드 가교결합체의 항균 효과

  • Received : 2014.12.05
  • Accepted : 2014.12.15
  • Published : 2014.12.31


This study was investigated the antimicrobial activity of glutaraldehyde cross-linked glucosamine. Glutaraldehyde was used as a cross-linker which specifically combines an amine-group of molecules. To optimize the mixing ratio of glutaraldehyde and glucosamine, mixing ratio was set up 1:1, 2:1, 3:1 and 0.5:1 in molarity, respectively. The optimum mixing ratio of glucosamine and glutaraldehyde was found to be 3:1 using thin layer chromatography based on the production of complex. Glucosamine-glutaraldehyde cross-linked complex (Ggcc) revealed significant antimicrobial activity toward PWG than F1, both microbial strains were isolated from porcine semen as antibiotics resistance bacteria (ARB). These results clearly demonstrate that Ggcc has potential bactericidal activity toward ARB in porcine semen.


Glucosamine;Glutaraldehyde;Cross-linked;Antimicrobial activity;Porcine semen


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