Antibacterial Activity of Rhus javanica against the Fish Pathogens Vibrio ichthyoenteri and Streptococcus iniae

오배자(Rhus javanica) 추출물의 어병세균 Vibrio ichthyoenteri와 Streptococcus iniae에 대한 항균활성

  • Kim, Kyoung-Hoon (Department of Life Science and Biotechnology, Dong-eui University) ;
  • Kim, Ah Ra (Department of Life Science and Biotechnology, Dong-eui University) ;
  • Cho, Eun-Ji (Department of Life Science and Biotechnology, Dong-eui University) ;
  • Joo, Seong-Je (Department of Life Science and Biotechnology, Dong-eui University) ;
  • Park, Jong-Hoon (Department of Life Science and Biotechnology, Dong-eui University) ;
  • Moon, Ji-Young (Department of Life Science and Biotechnology, Dong-eui University) ;
  • Yum, Jong-Hwa (Department of Clinical Laboratory Science, Dong-eui University) ;
  • Kim, Tae Hoon (Department of Herbal Medicinal Pharmacology, Daegu Haany University) ;
  • Kwon, Hyun-Ju (Blue-Bio Industry RIC, Dong-eui University) ;
  • Lee, Hyun-Tai (Blue-Bio Industry RIC, Dong-eui University) ;
  • Kim, Young-Man (Department of Food Science and Nutrition, Dong-eui University) ;
  • Lee, Eun-Woo (Blue-Bio Industry RIC, Dong-eui University)
  • 김경훈 (동의대학교 생명응용학과) ;
  • 김아라 (동의대학교 생명응용학과) ;
  • 조은지 (동의대학교 생명응용학과) ;
  • 주성제 (동의대학교 생명응용학과) ;
  • 박종훈 (동의대학교 생명응용학과) ;
  • 문지영 (동의대학교 생명응용학과) ;
  • 염종화 (동의대학교 임상병리학과) ;
  • 김태훈 (대구한의대학교 한약재약리학과) ;
  • 권현주 (동의대학교 블루바이오 소재개발센터) ;
  • 이현태 (동의대학교 블루바이오 소재개발센터) ;
  • 김영만 (동의대학교 식품영양학과) ;
  • 이은우 (동의대학교 블루바이오 소재개발센터)
  • Received : 2014.01.17
  • Accepted : 2014.02.06
  • Published : 2014.02.28


The antibacterial activities of methanol extracts of 19 commercial herbal medicines were measured against the fish pathogens Vibrio ichthyoenteri and Streptococcus iniae, which cause several fish diseases. Rhus javanica showed the strongest antibacterial activity against V. ichthyoenteri and S. iniae. The methanol extract of R. javanica was extracted further using several organic solvents with different polarities. The extract from the ethyl acetate fraction showed strong activity against both fish pathogens. The minimum inhibitory concentration (MIC) of the R. javanica extract was $32{\mu}g/mL$ for V. ichthyoenteri and $128{\mu}g/mL$ for S. iniae. Further purification and isolation of the active compound (s) responsible for these activities and further study of the synergistic effect using combinations of antibiotics against pathogenic bacteria are needed.



Supported by : 동의대학교


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