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Extraction of Biomolcules by Ionic Liquids

이온성 액체를 이용한 생물분자의 추출

  • Lee, Woo Yun (Department of Chemical and Biological Engineering, Korea National University of Transportation) ;
  • Lee, Yong Hwa (Department of Chemical and Biological Engineering, Korea National University of Transportation) ;
  • Lee, Jun (Department of Chemical and Biological Engineering, Korea National University of Transportation) ;
  • Hong, Yeon Ki (Department of Chemical and Biological Engineering, Korea National University of Transportation)
  • 이우윤 (한국교통대학교 화공생물공학과) ;
  • 이용화 (한국교통대학교 화공생물공학과) ;
  • 이준 (한국교통대학교 화공생물공학과) ;
  • 홍연기 (한국교통대학교 화공생물공학과)
  • Received : 2014.11.04
  • Accepted : 2014.11.24
  • Published : 2014.11.30

Abstract

As an effective separation method for biomolecules, aqueous two-phase systems based on ionic liquids were suggested. Hydrophobic ionic liquids are more expensive and viscous in spite of their usage in the ionic liquid/water biphasic extraction compared with hydrophilic ionic liquids. In case of aqueous two-phase systems using hydrophilic ionic liquids, they can be diluted in aqueous phase. Experimental results show that aqueous two phase systems can be formed by adding appropriate amount of ionic liquids to aqueous salts solutions. The viscosity of ionic liquid aqueous phase is proportional to the cation chain length in ionic liquids. It is founded that the ionic liquid based aqueous two phase systems are effective for the separation of biomolecules such as acrylic acid.

Acknowledgement

Supported by : 한국교통대학교