Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
권호 표지
DOI QR코드

DOI QR Code

Nutritional Components and Physiological Activities of Cirsium setidens Nakai

고려엉겅퀴(곤드레)의 영양성분 및 생리활성

  • Lee, Ok-Hwan (Dept. of Food Science and Biotechnology, Kangwon National University) ;
  • Kim, Jae Hwan (Dept. of Food Science and Biotechnology, Kangwon National University) ;
  • Kim, Young Hyun (Dept. of Food Science and Biotechnology, Kangwon National University) ;
  • Lee, Young Jun (Dept. of Food Science and Biotechnology, Kangwon National University) ;
  • Lee, Jong Seok (Dept. of Food Science and Biotechnology, Kangwon National University) ;
  • Jo, Ju Hyun (Hurum Central Research Institute) ;
  • Kim, Bong Gyun (Hurum Central Research Institute) ;
  • Lim, Jae Kag (Dept. of Chemical Engineering and Biotechnology, Korea Polytechnic University) ;
  • Lee, Boo-Yong (Dept. of Food Science and Biotechnology, CHA University)
  • 이옥환 (강원대학교 식품생명공학과) ;
  • 김재환 (강원대학교 식품생명공학과) ;
  • 김영현 (강원대학교 식품생명공학과) ;
  • 이영준 (강원대학교 식품생명공학과) ;
  • 이종석 (강원대학교 식품생명공학과) ;
  • 조주현 ((주)휴럼 중앙연구소) ;
  • 김봉균 ((주)휴럼 중앙연구소) ;
  • 임재각 (한국산업기술대학교 생명화학공학과) ;
  • 이부용 (차의과대학교 식품생명공학과)
  • Received : 2014.02.11
  • Accepted : 2014.03.24
  • Published : 2014.06.30

Abstract

Cirsium setidens Nakai, a wild perennial, is widely consumed as a food and traditional medicine in Korea. In addition, diverse functionalities of C. setidens Nakai, including anti-inflammatory and antioxidant effects, have been reported. However, whether or not C. setidens Nakai and its major compound, pectolinarin have high nutritional value and functional properties remains unknown. This paper investigated the proximate compositions, mineral contents, hepatoprotective activities, hepatic fat accumulation inhibitory activities, and anti-inflammatory and anti-oxidant activities of C. setidens Nakai and its component parts, including of pectolinarin. The result showed that C. setidens Nakai and its major compounds have potential as a functional food material with natural antioxidant and anti-inflammatory activities.

Keywords

File

Download PDF

Acknowledgement

Supported by : 한국연구재단

References

  1. Wiseman H. 1996. Dietary influences on membrane function; importance in protection against oxidative damage and disease. J Nutr Biochem 7: 2-15. https://doi.org/10.1016/0955-2863(95)00152-2
  2. Shin DH. 1997. The study course and movement of natural antioxidant. Food Sci Ind 30: 14-21.
  3. Frankel EN. 1996. Antioxidants in lipid foods and their on food quality. Food Chem 57: 51-55. https://doi.org/10.1016/0308-8146(96)00067-2
  4. Morita N, Shimizu M, Arisawa M. 1973. Two new flavone glycosides from Cirsium lineare. Phytochemistry 12: 421-423. https://doi.org/10.1016/0031-9422(73)80032-9
  5. Rauen HM, Schriewer H. 1971. The antihepatotoxic effect of silymarin on liver damage in rats induced by carbon tetrachloride, d-galactosamine and allyl alcohol. Arzneimittelforschung 21: 1194-1201.
  6. Mourelle M, Muriel P, Favari L, Franco T. 1989. Prevention of CCl4-induced cirrhosis by silymarin. Fundam Clin Pharmacol 3: 183-191. https://doi.org/10.1111/j.1472-8206.1989.tb00449.x
  7. Ingelman-Sundberg M, Johansson I, Penttilä KE, Glaumann H, Lindros KO. 1988. Centrilobular expression of ethanol-inducible cytochrome P450 (IIE1) in rat liver. Biochem Biophys Res Commun 157: 55-60. https://doi.org/10.1016/S0006-291X(88)80010-X
  8. Ferenci P, Dragosics B, Dittrich H, Frank H, Benda L, Lochs H, Meryn S, Base W, Schneider B. 1989. Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatol 9: 105-113.
  9. Lee SH, Jin YS, Heo SI, Shim TH, Sa JH, Choi DS, Wang MH. 2006. Composition analysis and antioxidative activity from different organs of Cirsium setidens Nakai. Korean J Food Sci Technol 38: 571-576.
  10. Surh J, Kim JO, Kim MH, Lee JC, Lee BY, Kim MY, Yang HW, Yun S, Jeong HR. 2009. Nutritional properties, as food resources for menu development, of cubed snailfish, shaggy sea raven, and two kinds of wild vegetables that are staple products in Samcheok. Korean J Food Cookery Sci 25: 690-702.
  11. Lee WB, Kwon HC, Cho OR, Lee KC, Choi SU, Baek NI, Lee KR. 2002. Phytochemical constituens of Cirsium setidens Nakai and their cytotoxicity against human cancer cell lines. Arch Pharm Res 25: 628-635. https://doi.org/10.1007/BF02976934
  12. Lee SJ. 1966. Korean folk medicine. Seoul National University Press, Seoul, Korea. p 145-146.
  13. Ishida H, Umino T, Tsuji K, Kosuge T. 1987. Studies on antihemmorrhagic substances in herbs classified as hemostatics in Chinese medicine. Ⅶ. On the antihemorrhagic principle in Cirsium japonicum DC. Chem Pharm Bull (Tokyo) 35: 861-864. https://doi.org/10.1248/cpb.35.861
  14. Kang IJ, Ham SS, Chung CK, Lee SY, Oh DH, Choi KP, Do JJ. 1997. Development of fermented soysauce using Cirsium setidens Nakai and comfrey. J Korean Soc Food Sci Nutr 26: 1152-1158.
  15. Chang SY, Song JH, Kwak YS, Han MJ. 2012. Quality characteristics of Gondre tofu by the level of Cirsium setidens powder and storage. Korean J Food Culture 27: 737-742. https://doi.org/10.7318/KJFC/2012.27.6.737
  16. Suh JT, Ryu SY, Kim WB, Choi KS, Kim BH. 1996. Improvement of gemination rate by low temperature and development of effective shading cultivation of Cirsium setidens under rain shelter in highland. Korean J Plant Res 9: 151-156.
  17. Im HE, Yoe HK, Chang SY, Han MJ. 2012. Quality characteristics of Gondregaedduck by the level of Cirsium setidens and storage. Korean J Food Culture 27: 400-406. https://doi.org/10.7318/KJFC/2012.27.4.400
  18. Ham SS, Lee SY, Oh DH, Kim SH, Hong JK. 1997. Development of beverages drinks using mountain edible herbs. J Korean Soc Food Sci Nutr 26: 92-97.
  19. Park MJ, Choi JK, Kakishima M, Shin HD. 2011. First report of rust disease caused by Puccinia nishidana on Cirsium setidens. Plant Pathol J 27: 297. https://doi.org/10.5423/PPJ.2011.27.3.297
  20. Lee KC, Noh HS, Kim JW, Han SS. 2012. Physiological responses of Cirsium setidens and pleurospermum camtschaticum under different shading treatments. J Bio-Env Con 21: 153-161.
  21. Yoo SK, Bae YM. 2012. Phylogenetic and chemical analyses of Cirsium pendulum and Cirsium setidens inhabiting Korea. J Life Sci 22: 1120-1125. https://doi.org/10.5352/JLS.2012.22.8.1120
  22. Katiyar SK, Mantena SK, Meeran SM. 2011. Silymarin protects epidermal keratinocytes from ultraviolet radiation-induced apoptosis and DNA damage by nucleotide excision repair mechanism. PLoS One 6: e21410. https://doi.org/10.1371/journal.pone.0021410
  23. Lee DG, Kim HK, Park Y, Park SC, Woo ER, Jeong HG, Hahm KS. 2003. Gram-positive bacteria specific properties of silybin derived from Silybum marianum. Arch Pharm Res 26: 597-600. https://doi.org/10.1007/BF02976707
  24. Song MJ, Kim H. 2005. Taxonomic identities of Cirsium setidens, C. chanroenicum and C. toraiense. Korean J PI Taxon 35: 227-245.
  25. Hur SJ, Park EY, Ann MJ, Jang AR, Yang KS, Whang WK. 2010. A study on the whitening effects and HPLC pattern analysis of Cirsium setidens Nakai. Kor J Aesthet Cosmetol 8: 1-9.
  26. Kim EM. 2011. Antioxidant and anticancer effects of extracts and components from Artemisia princeps Pampanini and Cirsium setidens Nakai. J East Asian Soc Dietary Life 21: 871-876.
  27. An BJ, Lee JT, Lee SA, Kwak JH, Park JM, Lee JU, Son JH. 2004. Antioxidant effects and application as natural ingredients of Korean Sanguisorbae officinalis L. J Korean Soc Appl Biol Chem 47: 244-250.
  28. Lee SH, Heo SI, Li L, Lee MJ, Wang MH. 2008. Antioxidant and hepatoprotective activities of Cirsium setidens NAKAI against CCl4-induced liver damage. Am J Chin Med 36:107-114. https://doi.org/10.1142/S0192415X0800562X
  29. Colak Y, Tuncer I, Senates E, Ozturk O, Doganay L, Yilmaz Y. 2012. Nonalcoholic fatty liver disease: a nutritional approach. Metab Syndr Relat Disord 10: 161-166. https://doi.org/10.1089/met.2011.0145
  30. Noh H, Lee H, Kim E, Mu L, Rhee YK, Cho CW, Chung J. 2013. Inhibitory effect of a Cirsium setidens extracts on hepatic fat accumulation in mice fed a high-fat diet via the induction of fatty acid ${\beta}$-oxidation. Biosci Biotechnol Biochem 77: 1424-1429. https://doi.org/10.1271/bbb.130049
  31. Day CP, James OFW. 1998. Steatohepatitis: A tale of two "hits"? Gastroenterology 114: 842-845. https://doi.org/10.1016/S0016-5085(98)70599-2
  32. Lee SH, Jung MJ, Heo SI, Wang MH. 2009. Anti-inflammatory effect and HPLC analysis of extract from edible Cirsium setidens. J Korean Soc Appl Biol Chem 52: 437-442. https://doi.org/10.3839/jksabc.2009.076
  33. Nugroho A, Kim MH, Lim SC, Choi JW, Choi JS, Park HJ. 2011. Validation of high-performance liquid chromatography analysis on phenolic substances of Cirsium setidens and sedative effect of pectolinarin as the active principle. Nat Prod Sci 17: 342-349.
  34. Yoo YM, Nam JH, Kim MY, Choi J, Park HJ. 2008. Pectolinarin and pectolinarigenin of Cirsium setidens prevent the hepatic injury in rats caused by D-galactosamine via an antioxidant mechanism. Biol Pharm Bull 31: 760-764. https://doi.org/10.1248/bpb.31.760
  35. Martinez-Vazquez M, Ramirez Apan TO, Lastra AL, Bye R. 1998. A comparative study of the analgesic and anti-inflammatory activities of pectolinarin isolated from Cirsium subcoriaceum and linarin isolated from Buddleia cordata. Planta Med 64: 134-137. https://doi.org/10.1055/s-2006-957390
  36. Tundis R, Deguin B, Loizzo MR, Bonesi M, Statti GA, Tillequin F, Menichini F. 2005. Potential antitumor agents: flavones and their derivatives from Linaria reflexa Desf. Bioorg Med Chem Lett 15: 4757-4760. https://doi.org/10.1016/j.bmcl.2005.07.029
  37. Liu S, Zhang J, Li D, Liu W, Luo X, Zhang R, Li L, Zhao J. 2007. Anticancer activity and quantitative analysis of flavone of Cirsium japonicum DC. Nat Prod Res 21: 915-922. https://doi.org/10.1080/14786410701494686
  38. Liu S, Luo X, Li D, Zhang J, Qiu D, Liu W, She L, Yang Z. 2006. Tumor inhibition and improved immunity in mice treated with flavone from Cirsium japonicum DC. Int Immunopharmacol 6: 1387-1393. https://doi.org/10.1016/j.intimp.2006.02.002
  39. Li B, Wang Z, Fang JJ, Xu CY, Chen WX. 2007. Evaluation of prognostic markers in severe drug-induced liver disease. World J Gastroenterol 13: 628-632. https://doi.org/10.3748/wjg.v13.i4.628
  40. Yoshikawa T, Furukawa Y, Murakami M, Takemura S, Kondo M. 1982. Effects of vitamin E on D-galactosamineinduced or carbon tetrachloride-induced hepatotoxicity. Digestion 25: 222-229. https://doi.org/10.1159/000198836
  41. Qintero A, Pedraza CA, Siendones E, Kamal Elsaid AM, Colell A, Garcia-Ruiz C, Montero JL, De la Mata M, Fernandez-checa JC, Mino G, Muntane J. 2002. PGE1 protection against apoptosis induced by D-galactosamine is not related to the modulation of intracellular free radical production in primary culture of rat hepatocytes. Free Radic Res 36: 345-355. https://doi.org/10.1080/10715760290019372
  42. Mcmillan JM, Jollow DJ. 1992. Galactosamine hepatotoxicity: effect of galactosamine on glutathione resynthesis in rat primary hepatocyte cultures. Toxicol Appl Pharmacol 115: 234-240. https://doi.org/10.1016/0041-008X(92)90328-P
  43. Lim H, Son KH, Chang HW, Bae K, Kang SS, Kim HP. 2008. Anti-inflammatory activity of pectolinarigenin and pectolinarin isolated from Cirsium chanroenicum. Biol Pharm Bull 31: 2063-2067. https://doi.org/10.1248/bpb.31.2063

Cited by

  1. Stability of Ethanolic Extract from Cirsium setidens Nakai vol.31, pp.4, 2016, https://doi.org/10.13103/JFHS.2016.31.4.304
  2. Combined Treatment of Aqueous Chlorine Dioxide, Organic Acid, and Blanching for Microbial Decontamination of Wild Vegetables after Harvest vol.45, pp.2, 2016, https://doi.org/10.3746/jkfn.2016.45.2.277