- Volume 27 Issue 3
DOI QR Code
Repetitive Transcranial Magnetic Stimulation to Treat Depression and Insomnia with Chronic Low Back Pain
- Park, Eun Jung (Seoul ChukChuk Pain Hospital) ;
- Lee, Se Jin (Department of Anesthesiology and Pain Medicine, Soonchunhyang Seoul Hospital, College of Medicine, Soonchunhyang University) ;
- Koh, Do Yle (Godoil Spine and Pain Hospital) ;
- Han, Yoo Mi (Department of Anesthesiology and Pain Medicine, Soonchunhyang Seoul Hospital, College of Medicine, Soonchunhyang University)
- Received : 2013.10.18
- Accepted : 2014.05.12
- Published : 2014.07.01
Transcranial magnetic stimulation (TMS) is a noninvasive and safe technique for motor cortex stimulation. TMS is used to treat neurological and psychiatric disorders, including mood and movement disorders. TMS can also treat several types of chronic neuropathic pain. The pain relief mechanism of cortical stimulation is caused by modifications in neuronal excitability. Depression is a common co-morbidity with chronic pain. Pain and depression should be treated concurrently to achieve a positive outcome. Insomnia also frequently occurs with chronic lower back pain. Several studies have proposed hypotheses for TMS pain management. Herein, we report two cases with positive results for the treatment of depression and insomnia with chronic low back pain by TMS.
- Kelly GA, Blake C, Power CK, O'keeffe D, Fullen BM. The association between chronic low back pain and sleep: a systematic review. Clin J Pain 2011; 27: 169-81. https://doi.org/10.1097/AJP.0b013e3181f3bdd5
- Bair MJ, Robinson RL, Katon W, Kroenke K. Depression and pain comorbidity: a literature review. Arch Intern Med 2003; 163: 2433-45. https://doi.org/10.1001/archinte.163.20.2433
- Barker AT, Jalinous R, Freeston IL. Non-invasive magnetic stimulation of human motor cortex. Lancet 1985; 1: 1106-7.
- Simons W, Dierick M. Transcranial magnetic stimulation as a therapeutic tool in psychiatry. World J Biol Psychiatry 2005; 6: 6-25. https://doi.org/10.1080/15622970510029812
- Leung A, Donohue M, Xu R, Lee R, Lefaucheur JP, Khedr EM, et al. rTMS for suppressing neuropathic pain: a meta-analysis. J Pain 2009; 10: 1205-16. https://doi.org/10.1016/j.jpain.2009.03.010
- Rokyta R, Fricova J. Neurostimulation methods in the treatment of chronic pain. Physiol Res 2012; 61 Suppl 2: S23-31.
- Zaghi S, Heine N, Fregni F. Brain stimulation for the treatment of pain: a review of costs, clinical effects, and mechanisms of treatment for three different central neuromodulatory approaches. J Pain Manag 2009; 2: 339-52.
- Krishnan KR, France RD, Pelton S, McCann UD, Davidson J, Urban BJ. Chronic pain and depression. II. Symptoms of anxiety in chronic low back pain patients and their relationship to subtypes of depression. Pain 1985; 22: 289-94. https://doi.org/10.1016/0304-3959(85)90029-6
- Maletic V, Robinson M, Oakes T, Iyengar S, Ball SG, Russell J. Neurobiology of depression: an integrated view of key findings. Int J Clin Pract 2007; 61: 2030-40. https://doi.org/10.1111/j.1742-1241.2007.01602.x
- Paus T, Barrett J. Transcranial magnetic stimulation (TMS) of the human frontal cortex: implications for repetitive TMS treatment of depression. J Psychiatry Neurosci 2004; 29: 268-79.
- George MS, Lisanby SH, Avery D, McDonald WM, Durkalski V, Pavlicova M, et al. Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder: a sham-controlled randomized trial. Arch Gen Psychiatry 2010; 67: 507-16. https://doi.org/10.1001/archgenpsychiatry.2010.46
- George MS, Taylor JJ, Short EB. The expanding evidence base for rTMS treatment of depression. Curr Opin Psychiatry 2013; 26: 13-8. https://doi.org/10.1097/YCO.0b013e32835ab46d
- Tang NK, Wright KJ, Salkovskis PM. Prevalence and correlates of clinical insomnia co-occurring with chronic back pain. J Sleep Res 2007; 16: 85-95. https://doi.org/10.1111/j.1365-2869.2007.00571.x
- Jiang CG, Zhang T, Yue FG, Yi ML, Gao D. Efficacy of repetitive transcranial magnetic stimulation in the treatment of patients with chronic primary insomnia. Cell Biochem Biophys 2013; 67: 169-73. https://doi.org/10.1007/s12013-013-9529-4
- Lefaucheur JP. Use of repetitive transcranial magnetic stimulation in pain relief. Expert Rev Neurother 2008; 8: 799-808. https://doi.org/10.1586/14737220.127.116.119
- Barr MS, Farzan F, Davis KD, Fitzgerald PB, Daskalakis ZJ. Measuring GABAergic inhibitory activity with TMS-EEG and its potential clinical application for chronic pain. J Neuroimmune Pharmacol 2013; 8: 535-46. https://doi.org/10.1007/s11481-012-9383-y
- de Andrade DC, Mhalla A, Adam F, Texeira MJ, Bouhassira D. Neuropharmacological basis of rTMS-induced analgesia: the role of endogenous opioids. Pain 2011; 152: 320-6. https://doi.org/10.1016/j.pain.2010.10.032
- Loo CK, Mitchell PB. A review of the efficacy of transcranial magnetic stimulation (TMS) treatment for depression, and current and future strategies to optimize efficacy. J Affect Disord 2005; 88: 255-67. https://doi.org/10.1016/j.jad.2005.08.001
- Bretlau LG, Lunde M, Lindberg L, Unden M, Dissing S, Bech P. Repetitive transcranial magnetic stimulation (rTMS) in combination with escitalopram in patients with treatmentresistant major depression: a double-blind, randomised, sham-controlled trial. Pharmacopsychiatry 2008; 41: 41-7. https://doi.org/10.1055/s-2007-993210
- Machii K, Cohen D, Ramos-Estebanez C, Pascual-Leone A. Safety of rTMS to non-motor cortical areas in healthy participants and patients. Clin Neurophysiol 2006; 117: 455-71. https://doi.org/10.1016/j.clinph.2005.10.014
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- Analgesic effect of repetitive transcranial magnetic stimulation (rTMS) in patients with chronic low back pain vol.37, pp.8, 2016, https://doi.org/10.1002/bem.22001
- Repetitive transcranial magnetic stimulation: a potential therapeutic modality for chronic low back pain vol.30, pp.1, 2017, https://doi.org/10.3344/kjp.2017.30.1.71
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