DOI QR코드

DOI QR Code

A Synthesis of Novel Sulfur-Linked Fused Thienotriazolopyrimidine Derivatives

  • Received : 2014.06.16
  • Accepted : 2014.07.09
  • Published : 2014.08.20

Abstract

Keywords

Thienotriazolopyrimidine;1,2,4-Triazole;Tetracyclic;STAT-3

References

  1. Aaronson, D.; Horvath, C. Science 2002, 296, 1653. https://doi.org/10.1126/science.1071545
  2. Yu, H.; Pardoll, D.; Jove, R. S. Nat. Rev. Cancer 2009, 9, 798 https://doi.org/10.1038/nrc2734
  3. (d) Song, Y.-H.; Son, H. Y. J. Heterocycl. Chem. 2011, 48, 597. https://doi.org/10.1002/jhet.549
  4. (e) Song, Y.-H.; Moon, J. Heterocycl. Commun. 2011, 17, 135.
  5. (f) Song, Y.-H.; Son, H. Y. J. Heterocycl. Chem. 2010, 47, 1183. https://doi.org/10.1002/jhet.461
  6. (g) Son, H. Y.; Song, Y.-H. Bull. Korean Chem. Soc. 2010, 31, 2242. https://doi.org/10.5012/bkcs.2010.31.8.2242
  7. (h) Song, Y.-H.; Jo, B. S. J. Heterocycl. Chem. 2009, 46, 1132. https://doi.org/10.1002/jhet.186
  8. (i) Jo, B. S.; Son, H. Y.; Song, Y.-H. Heterocycles 2008, 75, 3091. https://doi.org/10.3987/COM-08-11465
  9. Rho, M. C.; Song, Y.-H.; Lee, S. W.; Park, C. S.; Oh, H. M. Novel Heterocyclic Compounds and Use Thereof. Korean Patent, Appl. 10-2013-0008307, 2013.
  10. Rose-John, S.; Waetzig, G. H.; Schller, J.; Gratzinger, J.; Seegert, D. Expert Opin. Ther. Targets 2007, 11, 613. https://doi.org/10.1517/14728222.11.5.613
  11. (b) Adachi, Y.; Yoshio-Hoshino, N.; Nishimoto, N. Curr. Pharm. Des. 2008, 14, 1217. https://doi.org/10.2174/138161208784246072
  12. (a) Lauria, A.; Abbate, I.; Patella, C.; Martorana, A.; Dattolo, G.; Almerico, A. M. Eur. J. Med. Chem. 2013, 62, 416. https://doi.org/10.1016/j.ejmech.2013.01.019
  13. (b) Rizk, O. H.; Shaaban, O. G.; El-Ashmawy, I. M. Eur. J. Med.Chem. 2012, 55, 85. https://doi.org/10.1016/j.ejmech.2012.07.007
  14. (c) Liu, Y.; Esteva-Font, C.; Yao, C.; Phuan, P. W.; Verkman, A. S.; Anderson, M. O. Bioorg. Med. Chem. Lett. 2013, 23, 3338. https://doi.org/10.1016/j.bmcl.2013.03.089
  15. (d) Guetzoyan, L. J.; Spooner, R. A.; Lord, J. M.; Roberts, L. M.; Clarkson, G. J. Eur. J. Med. Chem. 2010, 45, 275. https://doi.org/10.1016/j.ejmech.2009.10.007
  16. (e) Nagamatsu, T.; Ahmed, S.; Hossion, A. M. L.; Ohno, S. Heterocycles 2007, 73, 777. https://doi.org/10.3987/COM-07-S(U)58
  17. (a) Chen, Q.; Zhu, X.-L.; Jiang, L.-L.; Yang, G.-F. Eur. J. Med. 2008, 43, 595. https://doi.org/10.1016/j.ejmech.2007.04.021
  18. (b) Bali, U.; et al. Bioorg. Med. Chem. Lett. 2012, 22, 824. https://doi.org/10.1016/j.bmcl.2011.12.050
  19. (c) Almajan, G. L.; Innocenti, A.; Puccetti, L.; Manole, G.; Barbuceanu, S.; Saramet, I.; Scozzafava, A.; Supuran, C. T. Bioorg. Med. Chem. Lett. 2005, 15, 2347. https://doi.org/10.1016/j.bmcl.2005.02.088
  20. (d) Contour-Galcera, M. O.; Sidhu, A.; Plas, P.; Roubert, P. Bioorg. Med. Chem. Lett. 2005, 15, 3555. https://doi.org/10.1016/j.bmcl.2005.05.061
  21. (e) Micheli, F.; et al. J. Med. Chem. 2010, 53, 374. https://doi.org/10.1021/jm901319p
  22. (a) Whang, J.; Song, Y.-H. J. Heterocycl. Chem. 2013, 50, 603. https://doi.org/10.1002/jhet.1574
  23. (b) Lee, H. J.; Kim, S. M.; Song, Y.-H. Heterocycl. Commun. 2013, 19, 101.
  24. (c) Whang, J.; Song, Y.-H. Heterocycles 2012, 85, 155. https://doi.org/10.3987/COM-11-12371

Acknowledgement

Supported by : Korea Research Foundation