- Volume 24 Issue 1
The Correlation of Metabolic Syndrome Factors and Bone Mineral Density on Postmenopausal Osteoporosis Patients with Low Back Pain under Korean Medicine Treatment
- Lee, Jong Deok ;
- Kim, Dong Woung ;
- Kwon, Young Dal
- Received : 2013.12.31
- Accepted : 2014.01.21
- Published : 2014.01.31
Objectives The relationship between metabolic syndrome causes and bone mineral density (BMD) was explored by taking 60 female chronic low back pain patients with age 61 years old or elder having metabolic syndrome and osteoporosis as study subjects. Methods Fasting blood glucose, serum total-cholesterol, triglyceride and HDL were measured by biochemical tests. Anthropometric elements and blood pressure were measured. Results Average BMD and T-score of part number 1 to 3 of lumbar vertebra were estimated by Quantitative Computed Tomography (QCT). In order to find the relationship between clinical factors and osteoporosis, correlation analysis was done on T-score. Age (r=0.679, p<0.01) had significant negative correlation and weight (r=0.342, p<0.01) and height (r=0.475, p<0.01) had significant positive correlation. Blood glucose, blood pressure, total cholesterol, triglyceride, HDL and body mass index did not have significant correlation. BMD had negative correlation with age (r=0.317, p<0.05). Regression analysis was done by taking T-score as independent variables and taking other factors as dependent variables. It was possible to know that age (
Metabolic syndrome;Bone mineral density;Osteoporosis;Low back pain
- Hall III JW, Kennedy BJ. Idiopathic osteoporosis. Arch Int Med. 1991;18:448.
- Cho SH. Menopausal and osteoporosis. The Journal of the Korean Med Asso. 1992;35(5):587-98.
- Takuo Fujita. Recent advances on osteoporosis. The Journal of Korean Society of Endocrinology. 1990;5(2): 92-100.
- Claus Christiansen. The third symposium for osteoporosis in seoul. Cheil general hospital. 1995;43-5.
- Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes. 1988;37:1595-607. https://doi.org/10.2337/diab.37.12.1595
- Executive Summary of the Third report of the National Cholesterol Education program (NCEP) Expert Panel on Detection, Evaluation, and treatment of high Blood cholesterol in Adults (Adult Treatment Pannel III). JAMA. 2001;28:2486-97.
- Baldini. Benefits of 2 years of intense exercise on bone density, physical fitness, and blood lipids in early postmenopausal osteopenic women. Archives of Internal Medicine. 2005;164:1084-91.
- Yamaguchi T, Sugimoto T, Yano S, Yamauchi M, Sowa H, Chen Q, Chihara K. Plasma lipids and osteoporosis in postmenopausal women. A pilot study. J Am Geriatr Soc. 2003;(51):1510-1.
- Andrea Poli, Fiorenza Bruschi, Bruno Cesana, Monica Rossi, Rodolfo Paoletti, Pier Giorgio Crosignani. Plasma low-density lipoprotein cholesterol and bone mass densitometry in postmenopausal women. Obstet Gynecol. 2003;102:922-6. https://doi.org/10.1016/j.obstetgynecol.2003.07.004
- Mazess RB. On aging bone loss. Clin Orthopaed Relat Res. 1982;165:239-52.
- Morgan DB. Aging and osteoporosis in particular spinal osteoporosis. Clin Endocronol Metabol. 1973;1:187-210.
- Riggs BL, Wahner HW, Dunn WL, Mazess RB, Offord KP, Melton LJ. Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest. 1981; 67:328-35. https://doi.org/10.1172/JCI110039
- Saville PD. Changes in bone mass with age and alcoholism, J Bone Joint Surg. 1965;47A(3):492-99.
- John JB. Anderson. The role of nutrition in the functioning of skeletal tissue. Nutrition Reviews. 1992;50(12): 388-94.
- Daiell H. Osteoporosis of the slender smoker. Ach Intern Med. 1976;13:298.
- Schindler AE, Ebert A, Friedrich E. Conversion of and rostendione to estron by human fat tissue. J Clin Endocrinol Metab. 2005;32.
- Carranza-lira S, Rosas N, Murillo A, Martinez N, Santos J. Osteoporosis in post menopausal women (mexico City) 1. risk factor. Int J Fertil Women Med. 2002;47(1):22-5.
- Stolk RP, Hoes AW, Pols HA, Hofman A, DeJong PT, Lamberts SW, Grobbee DE. Insulin, hypertension and anti-hypertensitive drugs in elderly patients. J Hypertens. 1996;14(2):234-42.
- Cui LH, Shin MH, Chung EK. Association between bone mineral densities and serum lipid profile of pre and post-menopausal women in South Korea. Osteoporosis Int. 2005;16:1975-81. https://doi.org/10.1007/s00198-005-1977-2
- D'Amelio P, Pescarmona GP, Gariboldi A, Isaia GC. High density lipoproteins (HDL) in women with postmenopausal osteoporosis: a preliminary study. Menopause. 2001;8:429-32. https://doi.org/10.1097/00042192-200111000-00008
- Adami S, Brage V, Zamboni M. Relationship between lipids and bone mass in 2 cohorts of healthy women and men. Calcif Tissue Int. 2004;74:136-42. https://doi.org/10.1007/s00223-003-0050-4
- Poli A, Bruschi F, Cesana B, Rossi M, Paoletti R, Crosignani PG. Plasma low-density lipoprotein cholesterol and bone mass densitometry in postmenopausal women. Obste & Gynecol. 2003;102:922-6. https://doi.org/10.1016/j.obstetgynecol.2003.07.004
- Tanko LB, Christiansen C, Cox DA, Geiger MJ, McNabb MA, Cummings SR. Relationship between osteoporosis and cardiovascular disease in postmenopausal women. Journal of Bone & Mineral Research. 2005;20(11):1912-20. https://doi.org/10.1359/JBMR.050711
- Parhami F, Garfinkel A, Demer LL. Role of lipids in osteoporosis. Arteriosclerosis, Thrombosis & Vascular Biology. 2000;20(11):2346-8. https://doi.org/10.1161/01.ATV.20.11.2346