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Influence of Iodinated Contrast Media and Paramagnetic Contrast Media on Changes in Uptake Counts of 99mTc

  • Cho, Jae-Hwan (Department of International Radiological Science, Hallym University of Graduate Studies) ;
  • Lee, Jin-Hyeok (Department of International Radiological Science, Hallym University of Graduate Studies) ;
  • Park, Cheol-Soo (Department of Radiological Science, Hallym Polytechnic University) ;
  • Lee, Sun-Yeob (Department of Radiological Science, Hallym Polytechnic University) ;
  • Lee, Jin (Department of International Radiological Science, Hallym University of Graduate Studies) ;
  • Moon, Deog-Hwan (Department of Public Health, Graduate School, Inje University) ;
  • Lee, Hae-Kag (Department of Computer Science and Engineering, Soonchunhyang University)
  • 투고 : 2014.05.29
  • 심사 : 2014.06.23
  • 발행 : 2014.09.30

초록

The purpose of this study is to figure out how uptake counts of technetium ($^{99m}Tc$) among radioisotopes in the human body are affected if computed tomography (CT), magnetic resonance imaging (MRI) and isotope examination are performed consecutively. $^{99m}Tc$ isotope material, iodinated contrast media for CT and paramagnetic contrast media for magnetic resonance (MR) were used as experimental materials. First, $^{99m}Tc$ was added to 4 cc normal saline in a test tube. Then, 2 cc of CT contrast media such as $Iopamidol^{(R)}$ and $Dotarem^{(R)}$ were diluted with 2 cc normal saline, and 2cc of MRI contrast media such as $Primovist^{(R)}$ and $Gadovist^{(R)}$ were diluted with 2 cc normal saline. Each distributed contrast media was a total of 4 cc and included 10m Ci of $^{99m}Tc$. A gamma camera, a LEHR (Low energy high resolution) collimator and a pin-hole collimator were used for image acquisition. Image acquisition was repeated a total of 6 times and 120 frames were obtained and uptake counts of $^{99m}Tc$ were measured (from this procedure). In this study, as a result of measuring the uptake counts of $^{99m}Tc$ using the LEHR collimator, the uptake counts were less measured in all contrast media than normal saline as a reference. In particular, the lowest uptake counts were measured when $Gadovist^{(R)}$, contrast media for MRI, was used. However, the result of measuring the uptake counts of $^{99m}Tc$ using the pin-hole collimator showed higher uptake counts in all contrast media, except for $Iopamidol^{(R)}$, than normal saline as a reference. The highest uptake counts were measured particularly when $Primovist^{(R)}$, contrast media for MRI, was used. In performing the gamma camera examination using contrast media and $^{99m}Tc$, it is considered significant to check the changes in the uptake counts to improve various diagnosis values.

과제정보

연구 과제 주관 기관 : Soonchunhyang university

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