- Volume 16 Issue 17
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Leukemia in Iran: Epidemiology and Morphology Trends
- Koohi, Fatemeh (Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences) ;
- salehiniya, Hamid (Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences) ;
- Shamlou, Reza (Department of Elder Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences) ;
- Eslami, Soheyla (Department of Elder Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences) ;
- Ghojogh, Ziyaeddin Mahery (Department of Elder Nursing, School of Nursing and Midwifery, Iran University of Medical Sciences) ;
- Kor, Yones (Department of Elder Nursing, School of Nursing and Midwifery, Iran University of Medical Sciences) ;
- Rafiemanesh, Hosein (Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences)
- Published : 2015.12.03
Background: Leukemia accounts for 8% of total cancer cases and involves all age groups with different prevalence and incidence rates in Iran and the entire world and causes a significant death toll and heavy expenses for diagnosis and treatment processes. This study was done to evaluate epidemiology and morphology of blood cancer during 2003-2008. Materials and Methods: This cross-sectional study was carried out based on re-analysis of the Cancer Registry Center report of the Health Deputy in Iran during a 6-year period (2003 - 2008). Statistical analysis for incidence time trends and morphology change percentage was performed with joinpoint regression analysis using the software Joinpoint Regression Program. Results: During the studied years a total of 18,353 hematopoietic and reticuloendothelial system cancers were recorded. Chi square test showed significant difference between sex and morphological types of blood cancer (P-value<0.001). Joinpoint analysis showed a significant increasing trend for the adjusted standard incidence rate (ASIR) for both sexes (P-value<0.05). Annual percent changes (APC) for women and men were 18.7 and 19.9, respectively. The most common morphological blood cancers were ALL, ALM, MM and CLL which accounted for 60% of total hematopoietic system cancers. Joinpoint analyze showed a significant decreasing trend for ALM in both sexes (P-value<0.05). Conclusions: Hematopoietic system cancers in Iran demonstrate an increasing trend for incidence rate and decreasing trend for ALL, ALM and CLL morphology.
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