The Effects of Exercise-Cognitive Combined Dual-Task Program on Cognitive Function and Depression in Elderly with Mild Cognitive Impairment

운동·인지 이중과제 프로그램이 경도인지장애 노인의 인지기능 및 우울에 미치는 영향

Kim, Kyoungah;Kim, Oksoo

  • Received : 2015.10.01
  • Accepted : 2015.12.12
  • Published : 2015.12.31


Purpose: This study was to develop and verify the effects of the exercise-cognitive combined dual-task training program on cognitive function and depression of the elderly with mild cognitive impairment (MCI). Methods: A non-equivalent control group pretest-posttest design was used. The participants were assigned into two groups: an experimental group receiving an exercise-cognitive combined dual-task (n=20) and a control group receiving a simple-task (n=18). After 8 weeks of intervention (2 days per week), the change in depression and cognitive functions were compared between the groups. Results: General cognitive function (t=-2.81, p=.011), frontal cognitive function (Z=-3.50, p<.001), attention/working memory function (U=-2.91, p=.004), depression (t=4.96, p<.001) of the experimental group were significantly increased than those of the control group. Conclusion: The findings of the study showed that an exercise-cognitive combined dual-task program for MCI was effective in improving general cognitive function, frontal and executive function, attention/working memory function, and reducing depression.


Mild cognitive impairment;Cognitive function;Depression;Dual-task program


  1. Ministry of Health & Welfare. 2012 Dementia prevalence rate survey [Internet]. Seoul: Ministry of Health & Welfare; 2012 [cited 2013 May 2]. Available from:
  2. Winblad B, Palmer K, Kivipelto M, Jelic V, Fratiglioni L, Wahlund LO, et al. Mild cognitive impairment-beyond controversies, towards a consensus: report of the international working group on mild cognitive impairment. Journal of International Medicine. 2004;256(3):240-6.
  3. Panza F, Frisardi V, Capurso CDA, Colacicco AM, Imbimbo BP et al. Late-life depression, mild cognitive impairment and dementia: possible continuum?. American Journal Geriatric Psychiatry. 2010;18(2):98-116.
  4. Bremner JD, Vythilingam M, Vermetten E, Vaccarino V, Charney DS. Deficits in hippocampal and anterior cingulate functioning during verbal declarative memory encoding in midlife major depression. The American Journal of Psychiatry. 2004;161(4):637-45.
  5. Chui W, Cheung E, Lam L. Neuropsychological profiles and short-term outcome in late-onset depression. Geriatric Psyciatry. 2011;26(5):458-65.
  6. Kim WY, Han CH, Heo EJ, Kang HW, Jeon WK. A review of non-pharmacological intervention efficacy in patients with mild cognitive impairment. Journal of Oriental Neuropsychiatry. 2011;22(3):1-11.
  7. Lee YM, Park NH. The effects of dementia prevention program on cognition, depression, self-esteem and quality of life in the elderly with mild cognitive disorder. Korean Society of Adult Nursing. 2007;19(5):104-14.
  8. Kim CM, Park YS, Kim SH. Analysis of trends in non-pharmacological studies for elders with dementia in korea. Journal of Gerontological Nursing. 2012;14(2):129-41.
  9. Ji EJ, Kim OS. Effect of the laughter therapy combined with cognitive reinforcement program for the elderly with mild cognitive impairment. Korean Society of Adult Nursing. 2014;26(1):34-45.
  10. Springer S, Gilade N, Peretz C, Yogev G, Simon M, Hausdorff K. Dual-tasking effects jon gait variability: the role of aging, falls, and executive function. Movement Disorders. 2006;21(7):950-7.
  11. Makizako H, Doi T, Shimada H, Yoshida D, Takayama Y, Suzuki T. Relationship between dual-task performance and neurocognitive measures in older adults with mild cognitive impairment. Geriatrics & Gerontology International. 2013;13(2):314-21.
  12. Erickson KI, Colcombe SJ, Wadhwa R, Bherer L, Peterson MS, Scalf PE, et al. Training-induced functional activation changes in dual-task processing: an FMRI study. Cerebral Cortex. 2007;17(1):192-204.
  13. Lee BT, Lee KM. Neural basis involved in the interference effects during dual task: interaction between calculation and memory retrieval. Korean Journal of Cognitive Science. 2007;18(2):159-78.
  14. Michael S, Tania Z, Peter O, Klaus H.(2010). Dual-task performances can be improved in patients with dementia: a randomized controlled trial. Neurology. 2010;74(24):1961-8.
  15. Kim HJ. The efficacy of the combined program of exercise and cognitive rehabilitation for the elderly people with mild dementia. [dissertation]. Seoul: Korea University; 2010.
  16. Kim GY, Han MR, Lee HG. Effect of dual-task rehabilitative training on cognitive and motor function of stroke patients. Journal of Physical Therapy Science. 2014;26(1):1-6.
  17. Park KS, Jung HY, So SY, Park YH, Yang HJ, Jung KR, et al. The effects of the activity program for preventing dementia against depression, cognitive function, and quality of life for the elderly. Journal of Oriental Neuropsychiatry. 2013;24(4):353-62.
  18. Lee JY, Lee DW, Cho SJ, Na DL, Jeon HJ, Kim SK, et al. Brief screening for mild cognitive impairment in elderly outpatient clinic: validation of the korean version of the montreal cognitive assessment. Journal of Geriatric Psychiatry and Neurology. 2008;21(2):104-10.
  19. Kang YO, Jang SM, Na DL. Seoul neuropsychological screen battery-II (SNSB-II). Seoul: Human Brain Research & Consulting; 2012.
  20. Jung IK, Kawk DI, Shin DK, Lee MS, Lee HS, Kim JY. A reliability and validity study of geriatric depression scale. Korean Neuropsychiatric Association. 1997;36(1):103-12.
  21. Kim HJ, Park S, Kim JH, Cho EH, Oh JS, Lee E, et al. Effect of pilates-combined exercise program on blood markers of mild cognitive impairment. The Korean Journal of Growth and Development. 2013;21(4):287-92.
  22. Leonie J, Martine S, Sandra W, Marie-Eve B, Yves T, Carol H, et al. Efficacy of a cognitive training programme for mild cognitive impairment: results of a randomized controlled study. Neuropsychological Rehabilitation. 2010;20(3):377-405.
  23. Andrea S, Juan MV, Marie S, Valerie HB, Bernard P, Bruno D. Frontal assessment battery and differential diagnosis of frontotemporal dementia and alzheimer disease. Archives Neurology. 2004;61(7):1104-7.
  24. Hikaru T, Yasuyuki T, Rui N, Hiroshi H, Atsushi S, Yuka K, et al. Effects of multitasking-training on gray matter structure and resting state neural mechanisms. Human Brain Mapping. 2014;35(8):3646-60.
  25. Han JH, Ko SG, Kwon JH, Cho IH, Ahn SM, Han CS, Park MH. Efficacy of a multifactorial cognitive ability enhancement program in MCI(mild cognitive impairment). The Korean Journal of Clinical Psychology. 2008;27(4):805-21.
  26. Hyndman D, Pickering RM, Ashburn A. Reduced sway during dual task balance performance among people with stroke at 6 and 12 months after discharge from hospital. Neurorehabilitaion & Neural Repair. 2009;23(8):847-54.
  27. Kizony R, Levin MF, Hughey L, Perez C, Fung J. Cognitive load and dual-task performance during locomotion post stroke: a feasibility study using a functional virtual environment. Physical Therapy. 2010;90(2): 252-60.
  28. Kang WG, Kang MH, Yang JL, Koo EJ, Kim SK. The comparison of EEG activity by computer assisted cognitive rehabilitation program in the normal elderly and the elderly with dementia. The Journal of Korean Society of Occupational Therapy. 2009;17(3):1-13.
  29. Kim MS. Development and effect of a cognitive intervention program. [dissertation]. Daejon: Chungnam National University; 2014.
  30. Kim DY, Yang EA. The effect of therapeutic music activity upon mood state and powerlessness in the elderly with mild cognitive impairment. Korean Music Therapy Association. 2013;15(2):73-94.