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피톤치드를 함유하고 있는 의류소재가 아토피에 미치는 영향

김의화
Kim, Eui Hwa

  • 투고 : 2015.11.02
  • 심사 : 2015.12.04
  • 발행 : 2015.12.31

초록

In this study, we investigated the effects of phytoncide-containing 100% cotton fabrics on the improvement of atopic dermatitis, through preclinical trials. The finishing agents used for testing were obtained by emulsification (S2), by capsulation (S4) using phytoncide extracted with supercritical $CO_2$, and by capsulation using solvent-extracted phytoncide (S3). The supercritically extracted phytoncide was used for in vitro testing. In the in vitro test, cytotoxicity occurred at the phytoncide concentrations of 0.1% and 0.5% in stained HaCaT cells and at 0.1% concentration in stained Raw 264.7 cells. In the in vivo test, the infiltration of inflammatory cells into skin tissue was significantly reduced in the S3 and S4 groups relative to the positive comparison group (Positive) of atopic dermatitis. Moreover, from results of the western blot and immunohistochemistry assays of tested skin tissue, we were able to confirm a reducing pattern of the markers related to keratogenesis.

키워드

atopic dermatitis;phytoncide;capsulation;emulsification;in vitro test;in vivo test

참고문헌

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