DOI QR코드

DOI QR Code

Korean Medicine Treatment for 326 patients with Genital Warts : Retrospective Chart Review

성기사마귀환자 326명의 한의학적 치료에 대한 후향적 연구

  • Received : 2015.09.09
  • Accepted : 2015.11.06
  • Published : 2015.11.25

Abstract

Purpose : To observe effects of Korean Medicine treatment for genital warts.Methods : In a single private clinic from February 2014 to February 2015, we did retrospective chart review for 326 patients with genital warts who had been treated by Korean Medicine. Korean Medicine treatment included herbal treatment and herbal ointment.Results : A total of 326 patients were enrolled in this study: 62.7%(n=219) male, 32.8%(n=107) female. In the type of diagnosis, new diagnosis was 45.4%(n=148) and recurrent disease was 54.6%(n=178). Complete clearance was achieved 63.2%(n=206) and treatment period was 3.5 months(range:1-9). Partial clearance-good was 15%(n=49), partial clearance-poor was 4.9%(n=16), non response was 16.9%(n=55) and the average treatment period was 4.3 months(range:1-14). In complete clearance group, female and the prevalence of less than 1 year were statistically significant(p<0.05). There was no recurrence of genital warts after TKM treatment during follow-up period(4-13months).Conclusion : This study suggest that Korean Medicine may be an effective treatment for genital warts.

Keywords

Genital warts;Condyloma acuminatum;Korean Medicine

References

  1. Han JH. Recommended managements for the male human papillomavirus infection. Korean J Urogenit Tract Infect Inflamm. 2014;9(2):79-85. https://doi.org/10.14777/kjutii.2014.9.2.79
  2. Kim SH, Lee GY, Park TJ, Kim JS, Kim YM, O HS. Factors related to human papilloma virus infection rate in womem. Korean J Fam Med. 2009;30:972-78. https://doi.org/10.4082/kjfm.2009.30.12.972
  3. Hong SH, Lee DK, Shin HL. Prevalence of human pailloma infection in women in South korea. Korean J. Cytopathol. 2004;15(1):17-27.
  4. World Health Organization. Vaccines against human papillomavirus. World Health Organization 2010. Available from URL:http://www.who.int/vaccines/en/hpvrd.sht ml/shtml/shtml
  5. Derkay CS, Wiatrak B. Recurrent respiratory papillomatosis: a review. Laryngoscope. 2008;118:1236-47. https://doi.org/10.1097/MLG.0b013e31816a7135
  6. Schiffman M. Integration of human papillomavirus vaccination, cytology, and human papillomavirus testing. Cancer Cytopathology. 2007;111:145-53. https://doi.org/10.1002/cncr.22751
  7. Moon SB, Moon SH, Park KJ. Detection and typing of human papillomavirus in anal condyloma acuminatum of HPV-positive patients. J Koean Surg Soc. 2010;78:111-5. https://doi.org/10.4174/jkss.2010.78.2.111
  8. Lee JH, Kim CW, Kim SS. Preliminary study of intralesional bleomycin injection for the treatment of genital warts. Ann Dermatol. 2015;27:239-41. https://doi.org/10.5021/ad.2015.27.2.239
  9. Park SY, Kim CD, Kim CW, Lee KS. Combination therapy with pulsed dye laser and intralesional bleomycin for the treatment of recalcitrant warts. Korean J Dermatol. 2005;43:638-42.
  10. Yoon JH, Choi JE, Ahn HH, Kye YC, Seo SH. 5% Therapeutic use of imiquimod cream. Korean J Dermatol. 2011;49:993-1001.
  11. Sonnex C, Scholefield JH, Kocjan G, Kelly G, Whatrup C, Mindel A et al. Anal human papillomavirus infection in heterosexuals with genital warts: prevalence and relation with sexual behaviour. BMJ. 1991;303:1243. https://doi.org/10.1136/bmj.303.6812.1243
  12. Park SJ, Seo JH, Ha SH, Jung GW. Prevalence and determinants of high-risk human papillomavirus infection in male genital warts. Korean J Urol. 2014;55:207-12. https://doi.org/10.4111/kju.2014.55.3.207
  13. Pful D, Silva MD, Micha JP, Douglas G. Management of condyloma acuminata. J Am Acad Dermatol. 1985;13:457-63. https://doi.org/10.1016/S0190-9622(85)70189-2
  14. Stanley M. Immune responses to human papillomavirus. Vaccine. 2006;24:16-22. https://doi.org/10.1016/j.vaccine.2005.09.002
  15. Lee KS, Jeong EJ, Yoon JS, Kim SH, Hwong JS. A case of huge condyloma acuminatum during pregnancy. Korean J Obstet Gynecol. 1993;46(4):829-33.
  16. Heo J. Donguibogam(Principles and Practice of Eastern Medicine), Bubin publishers co. 1999:824-5.
  17. Textbook Compilation Committee of Nationala University of Traditional Korean Dermatology & Surgery. Text of Traditional Korean Dermatology & Surgery. 2007:432-4.
  18. Moon SH, Lee MW, Paek JH, Kang MS, Kim JS, Yu HJ. Vestibular papillomatosis mimicking condyloma acuminatum. J. Rheumatic Dis. 2014;21:87-90. https://doi.org/10.4078/jrd.2014.21.2.87
  19. Keating MA, Young RH, Carr CP, Nikrui N, Heney NM. Condyloma acuminatum of the bladder and ureter: case report and review of the literature. J Urol. 1985;133:465-7. https://doi.org/10.1016/S0022-5347(17)49027-6
  20. Korean Society of Obstetrics and Gynecology. Gynaecology, the third edition. Seoul:Calvin P. 1997:306-7.
  21. Ryu HJ, Kim GN, Kim JW. Pulsed dye laser treatment of anogenital condyloma acuminate in a child. Korean J dermatol. 2002;40(3):324-6.
  22. Kim YJ, Byon CK, Kim ES, Kim HJ, Jeong IH, An WS et al. A case of condyloma acuminata in a virgin systemic lupus erythematosus patient. Korean J Rheum Dis. 2014;21(2):88-90.
  23. Salavastru CM, Niculescu MC, Zota A, Tiplica GS. Epidemiological aspects of genital warts in Romania – a 2012 retrospective survey. Maedica J Clinical Medicine. 2014;9(2):144-50.
  24. Kim HC. Herbal Pharmacology. Seoul:Jip mun dang. 2008:227-9.
  25. Lee KY, Lee E, Cho NK. Two cases report of verruca plana that developed after laser hair removal. J Korean Med Ophthalmol Otolaryngol Dermatol. 2015;28(2):112-20. https://doi.org/10.6114/jkood.2015.28.2.112
  26. Liu SQ. Treatment of genital warts with microwave and zini xizo decoction of 84cases. J of External Therapy of TCM. 2001;4:9.
  27. Lu JY. Treatment of genital warts by fuzheng jiedu decoction: A clinical observation of 30cases and mechanism research. Gansu J of TCM. 2007;7:58-9.
  28. Mario M, Fabiana G. Treatment of genital lesions with diode laser vaporization. BMC Urology. 2015;15:39-45. https://doi.org/10.1186/s12894-015-0033-6
  29. Ryu HJ, Kim GN, Kim JW. Pulsed dye laser treatment of anogenital condyloma acuminate in a child. Korean J dermatol. 2002;40(3):324-6.

Cited by

  1. A Case of Anal and Perianal Condyloma Acuminatum in a 2 Years Old Boy vol.29, pp.2, 2016, https://doi.org/10.6114/jkood.2016.29.2.180