The Effect of Sub-chronic Whole-Body Exposure to a 1,950 MHz Electromagnetic Field on the Hippocampus in the Mouse Brain

  • Son, Yeonghoon ;
  • Jeong, Ye Ji ;
  • Kwon, Jong Hwa ;
  • Choi, Hyung-Do ;
  • Pack, Jeong-Ki ;
  • Kim, Nam ;
  • Lee, Yun-Sil ;
  • Lee, Hae-June
  • Received : 2015.04.29
  • Accepted : 2015.07.06
  • Published : 2015.07.31


The increasing use of mobile phones has raised public concern about the possible biological effects of radiofrequency electromagnetic field (RF-EMF) exposure on the human brain. To investigate the potential effect of RF-EMF exposure on the brain, we examined the behaviors and hippocampal morphology of C57BL/6 mice after sub-chronic exposure to RF-EMFs with a relatively high SAR level (5.0 W/kg). We applied a 2-hour daily exposure of WCDMA 1,950 MHz using a reverberation chamber that was designed for whole-body exposure for 60 days. In the behavioral tests, RF-EMF did not alter the physical activity or long-term memory of mice. Moreover, no alteration was found in the neuronal and glial cells in the hippocampus by RF-EMFs. In this study, we showed that sub-chronic whole body RF exposure did not produce memory impairment and hippocampal morphological alteration in C57BL/6 mice.


Hippocampus;Memory;Mobile Phone;Radiofrequency Electromagnetic Field;Sub-chronic Exposure


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Grant : Study on the EMF exposure control in smart society

Supported by : IITP