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Clinical Study of the Effects of Gwibi-tang and Danggwisusan on Traffic Accident Patients with Acute Cervicolumbar Disorder

급성 경·요추 염좌로 진단된 교통사고 환자에서 귀비탕(歸脾湯)과 당귀수산(當歸鬚散)의 효과에 대한 임상 연구

  • Received : 2015.06.22
  • Accepted : 2015.07.07
  • Published : 2015.07.31

Abstract

Objectives This study was designed to compare the effects Gwibi-tang herbal-medication with Danggwisusan herbal-medication for patients with acute cervical and lumbar sprains due to a traffic accident. Methods This study was carried out on 119 acute cervical & lumbar sprain patients by traffic accident. We divided these patients into 2 groups. Group A was treated with Gwibi-tang and Group B was treated with Danggwisusan three times a day for three days. Each patient was treated with acupuncture, physical therapy and two types of herbal-medication. We measured the numerical rating scale (NRS) at two time points : pre-treatment (Tx). and post-Tx. Results 1. The NRS scores significantly decreased after treatment in all patients. 2. The changed NRS scores of nuchal pain showed a borderline significant difference between Group A and Group B (p=0.067). 3. In sub-group analysis, Gwibi-tang showed a greater effect on NRS scores of lumbago pain in female patients (p=0.068) and patients under 30s (p=0.054) compared to Danggwisusan. Conclusions In this study, both types of herbal-medication; Gwibi-tang and Danggwisusan were highly effective on acute cervical and lumbar sprain patients. Especially Gwibi-tang (Group A) was more effective than Danggwisusan (Group B) in reducing the initial nuchal pain. Also Gwibi-tang was more effective for lumbago pain in female and patients under 30s.

Keywords

Gwibi-tang herbal-medication;Danggwisusan herbal-medication;Acute cervical & lumbal sprain;Traffic Accident

References

  1. Traffic Accident Analysis System. Traffic Accident Statistical Analysis. Seoul:the Road Traffic Authority. 2013:7,351.
  2. Seo Young Park, Yun Kyu Lee, Jae Su Kim, Seong Chul Lim, Bong Hyo Lee, Tae Young Jung, Il Do Ha, Sang Won Han, Kyung Min Lee. Survey of Oriental Medical Care for Traffic Accident Patients with Automobile insurance; 544 Cases Report. Journal of Korean acupuncture & moxibustion medicine society. 2009;26(3):2.
  3. The Society of Korean Medicine Rehabilitation. Korean Rehabilitation Medicine. 3rd edition. Seoul:Gunja Publisher. 2011:15,204.
  4. Hee Guen Jo, Ae Ryeon Park, Young Bum Kee, Dae Hee Kang, Jin Bong Choi, Jae Uk Sul. A Clinical Trial on the Blood Stasis and Efficacy of Kyejibokryong-whan (Guizhifuling-wan) in the Patients with Motor Vehicle Accident. Journal of Korean Rehabilitation Medicine. 2011;21(3):45-55.
  5. Jo Minseo, Han Jaekyung, Kim Yunhee. The Clinical Study on 121 Traffic Accident Child Patients. The Journal of Korean Oriental Pediatrics. 2012;26(2):35-46. https://doi.org/10.7778/jpkm.2012.26.2.035
  6. Park Darnseo, Phil Kamheun, Lee Jeonghan, Kong Jaecheol, Baek Donggi, Song Yungsun, Kwon Youngmi. Survey of Satisfaction with Oriental Medical Care for Traffic Accident Patients ; 35 Cases Report. Journal of Korean Rehabilitation Medicine. 2008;18(3):99-118.
  7. Jeon Taedong, Oh Minseok. A Study on the Significance of Sanghanron Prescription in Traffic Accident Patient. Journal of Korean Rehabilitation Medicine. 2010;20(1):153-166
  8. Ki-Hyung Kim,Jin-Bong Choi. The Clinical Study on 51 cases with Traffic Accident. Journal of Korean Rehabilitation Medicine. 2001;12(4):91-9.
  9. Kim Kunhyung, Choi Yangsik, Nam Dongwoo, Kim Jongin, Cho Kiho, Choi Doyoung, Lee Jaedong. A Clinical Study on the Effect of Acupuncture and Bee-Venom Acupuncture for Patients with Chronic Whiplash Injury. Journal of Korean acupuncture & moxibustion medicine society. 2006;23(6):146-52.
  10. Yi Cheon. EuHakIbMun. Seoul:Bubin Publishers Co. 2009:2034.
  11. Heo jun. DongUiBoGam. Seoul:Donguibogam Publisher. 2005:99,1663-4.
  12. Herbal Medicine. Seoul:Younglimsa. 2007:154-5,236-8,396-9, 462-4,476-7,583-5,629-631.
  13. Go Kisuk, Kim Soonjoong, Oh Minseok, Song Taewon, Lee Cheol-Wan. Clinical research on how herbal treatments aftermath of traffic accidents and Case (260 people). Journal of Korean Rehabilitation Medicine. 1993;3(1):107-21.
  14. Eugene Kim, Yun-yeop Cha. A Study on Characteristics of Skin Resistance Variability(SRV) in the Traffic Accident Patients Using Dangkisoo-san. Journal of Korean Rehabilitation Medicine. 2008;18(3):120-32.
  15. Jeon Taedong, Lee Hangil, Hong Seoyoung, Heo Dongseok, Yoon Ilji, Oh Minseok. The Effectiveness of the Herb-medication based on abdominal diagnosis and-Dangkisoo-san(Dangguixu-san)Herb-medication for the Traffic Accident Patients. Journal of Korean Rehabilitation Medicine. 2007;17(4):209-18.
  16. Um Yonghwa. Jesaengbang. Beijing:People's Medical Publishing house Co. 1980:117.
  17. Xue-Ji. Neikezhaiyao. Jiangsu:Jiangsu science & technology press. 1985:41-2.
  18. Min Kyu Kim, Jeong Eun Heo, Sun Mi Park, Han Na Choi, In Seon Lee, Bong Hyun Kim, Yeon Kyeong Kang. Comparative Study of Normal Person and Traffic Accident Patient by DSOM. Korean Journal of Oriental Physiology and Pathology. 2009;23(1):245-50.
  19. Jaehwang Park. Effects of Stress Induced by Traffic Accidents on the Blood Concentrations of Cortisol, Glucose and Cytokines. Journal of Emergency Medicine. 1998;9(4):607-13.
  20. Dae Yong Son, Min Su Kim, Sung Woo Cho, Gyung Hoon Ko, Jung Hun Nam, Hee Duk An, In Seon Lee. The Correlation between the Stress with the Pain and Duration on the Traffic Accident Patients in Oriental Medical Hospital. Journal of Korean Rehabilitation Medicine. 2005;15(3):45-53.
  21. Choong Mo Moon, Wei Wan Whang. Experimental study on the anti - stress Effect of Guibitang. Journal of Kyung Hee University Medical Center. 1986;2(3):388-96.
  22. Lim Dongug, Yoo Dongyoul. Study on Effect to immunomodulatory of Gamiguibi-tang . The Journal Of Oriental Gynecology. 1999;12(2):253-80.
  23. JaeWoo Park, JinSeong Kim, BongHa Ryu, DongWon Park, KiWon Ryu. Antifatigue Effects of Guibi-tang Extract on Bat Muscle during Swimming. Journal of Oriental Chronic Diseases. 2000;6:162-73.
  24. Hakjae Kim, Junhyuk Choi, Seongwoo Lim. The difensive effect of Keuibitang on the injury of gastric mucous membrane of mouse by stress and ethanol. Journal of Korean Oriental Medicine.. 2003;24(1):155-68.
  25. No Dongjin, Jung lnchul. Study on Effect to Serotonin Metabolism of Gamiguibi-tang on P815 Cell. Journal of Oriental Neuropsychiatry. 2010;21(1):1-11.
  26. Minseong Gil. Modern Psychiatry. Seoul:Ilchokak. 2008:346-5.
  27. Hwang Jeonghyun, Ko Jaesang, Bae Jaeik, Koo Byungsoo, Kim Geunwoo. A Clinical Report of Three Patients with Acute Stress Disorder, Post-Traumatic Stress Disorder Treated by Oriental Medical Treatments. Journal of Oriental Neuropsychiatry. 2011;22(3):75-85. https://doi.org/10.7231/JON.2011.22.3.075
  28. Kim JH, Kim GH, Hwang KH. Monoamine Oxidase and Dopamine $\beta$-Hydroxylase Inhibitors from the Fruits of Gardenia jasminoides. Biomol Ther. 2012;20(2):214-19. https://doi.org/10.4062/biomolther.2012.20.2.214
  29. Juratsune H, Umigai N, Takeno R, Kajimoto Y, Nakano T. Effect of crocetin from Gardenia jasminoides Ellis on sleep: a pilot study. Phytomedicine. 2012;17(11):840-3.
  30. Sugiyama K, Muteki T, Kano T. The Japanese herbal medicine 'saiko-keishi-to' activates GABAA receptors of rat sensory neurons in culture. Neurosci Lett. 1996;216(3):147-50. https://doi.org/10.1016/0304-3940(96)13000-7
  31. Sungyou Hong, Sundong Park. The effect of Bupleurum falcatum L. on the catecholamines of depression rat model. Korea Journal of Herbology. 2003;18(4):245-53.
  32. Korean National Police Agency. Traffic Accident Statistics. Seoul:Korea Transportation Safety Authority. 2008:9-11,47.
  33. No Burae, Lee Eunyong. The Clinical Study on 34 Admission Patients due to Sequela of Traffic Accident. Journal of Pharmacopuncture. 2006;9(2):129-34. https://doi.org/10.3831/KPI.2006.9.2.129
  34. National Archives of Korea. Amendment of Automobile Liability Law Enforcement Ordinance. 1999. Available from: http://theme.archives.go.kr/next/pages/viewer/archiveViewer.jsp?rchiveEventId=0028811511&singleData=Y
  35. Chiang Suoyue, Park Jinwu, Shin Hyungun, Shin Junhuk, Lee Sangyoung, Koh Yongjun, Youn Hunjung, Ryu Hyeseon, Sul Jaeuk. Survey on Satisfaction of Korean Medicine Treatment in 131 Cases by Traffic Accident. Journal of Korean acupuncture & moxibustion medicine society. 2012;29(3):67-79.
  36. erling M, Jull G, Vincenzio B, Kenardy J. Characterization of acute whiplash-associated disorders : redfining "whiplash" and its management. Spine. 2004;29:182-8. https://doi.org/10.1097/01.BRS.0000105535.12598.AE
  37. Yun Kyung Song. Clinical Studies On 52 Cases Of Patient with Cervical Pain Caused by Traffic Accident. Journal of Korean Rehabilitation Medicine. 2000;10(1):45-55.
  38. Kim Eugene, Cha Yunyeop. Study on Characteristics of 7-Zone-Diagnostic System before and after Treatment in the Traffic Accident Patients and Patients with Low Back Pain or Nuchal Pain. Korean Journal Oriental Physiology & Pathology. 2009;23(1):255-31.
  39. SunMi Lee, ChungHee Kim. Precipitating Factors of Posttraumatic Stress Disorder and Psychological Characteristics in Bus Accident Victims. Korean Journal of Clinical Psychology. 2002;21(3):547-63.
  40. Kim Hyunwoo, Kim Hojun, Park Younghoi, Keum Dongho, Lee Myeongjong. Review of Post Traumatic Stress Disorder(PTSD) Symptoms in Traffic Accident Patients. Journal of Korean Rehabilitation Medicine. 2006;16(1):35-47.
  41. Eun Jung Kim, In Jae Kim, Dong Won Lee, Jong Sam Ryu, Seok Hong. Experimental Study on the Sedative Effect of Gagamguibitang. Journal of Oriental Neuropsychiatry. 2002;13(2):195-211.
  42. Jiang Keming. Concise Dictionary prescription. China: Shanghai Scientific and Technology Press. 1989:298.
  43. Han Chang, Park Jonghoon, Lee Jinhyuck, Min Kwansik, Han Kyungwan. Changes of quality of life and subjective stress after the oriental medicine treatment, among the patients who had visited hospital due to traffic accidents. Journal of Oriental Neuropsychiatry. 2010;21(2):17-28.
  44. Jung Kihoon, Hwang Heesang, Jeon Jaecheon, Kim Minseok, Park Jaeyeon, Lee Taeho, Lee Eunyong, Roh Jeongdu. Correlation Analysis of Subjective Stress Caused by Traffic Accident with Prognosis. Journal of Korean acupuncture & moxibustion medicine society. 2009;26(6):161-69.
  45. Sunhong Kim,Yunseub Sim. A Case With Traffic Accident Related Post-traumatic Stress Disorder. Journal of Oriental Neuropsychiatry. 2003;14(1):175-81.
  46. Sul Jaeuk, Kim Sejin, Chung Ilmoon, Kim Suyoun, Kim Kyeongok, Jang Hajeong, Choi Jinbong. Minnesota Multiphasic Personality Inventory Responses of Traffic Accidental Patients -Followed the Type of Traffic Accident, Posttraumatic Stress Disorder and Sex-. Journal of Korean Rehabilitation Medicine. 2006;16(3):137-48.
  47. Ko Kyoungmo, Choi Sunghun, Kim Jaesu, Park Seoyoung, Lee Yunkyu, Lee Yoonkyoung, Lee Kyungmin, Lee Bonghyo, Lim Seongchul, Choi Hongsik, Lee Eunkyung, Jung Taeyoung, Seo Jungchul. The Clinical Study On Posttraumatic Stress Disorder Patients due to a Serise of Traffic Accidents-SCL-90-R-. Journal of Korean acupuncture & moxibustion medicine society. 2007;24(6):63-68
  48. Andersson GBJ, Brown MD, Dvorak J, Herzog RJ, Malter A, McCullock JA, Saal JA, Spratt KF, Weinstein JN. Consensus summary on the diagnosis and treatment of lumbar disc herniation. Spine. 1996;21:75-8. https://doi.org/10.1097/00007632-199612151-00009
  49. Gyeongseok Lee, Wongyeong Bae. Diagnosis and Treatment of Low Back Pain. Seoul:Korea Medical book Publisher. 1998:46-7,81-6.
  50. Jeon Hyeonjeong, Kim Sunghwan, Kim Jeehyun, Lee Semin, Shin Hwayoung, Lee Yunkyu, Lee Bonghyo, Jung Taeyoung, Kim Jaesu, Lee Kyungmin, Lim Sungchul. The Clinical Study on 197 Cases with Patients of Neck Pain Caused by Traffic Accident. Journal of Korean acupuncture & moxibustion medicine society. 2010;27(2):143-54.
  51. Sternbach, R. A. Pain and 'hassles' in the United States: Findings of the Nuprin Pain Report. Pain. 1986;27(1):69-80. https://doi.org/10.1016/0304-3959(86)90224-1
  52. Susie Kim, Sangsub Ahn. The Effect of Korean version of Mindfulness-Based Stress Reduction Program on Chronic Pain of Workers. Korean Journal of Psychological & Social Issues. 2009;15(3):359-75.
  53. Lu, S. R., Lin, H. Y., Lin, K. C., & Lin, H. R. Quality of life in middleaged and older Taiwanese patients with rheumatoid arthritis. Journal of Nursing Research. 2008;16:121-130. https://doi.org/10.1097/01.JNR.0000387297.29796.ad
  54. Yejong Lee, Gumju Choi. The Effect of Korean Adult's Mental Health On QOL(Quality Of Life) -The Fifth Korea National Health and Nutrition Examination Survey, 2010.. Journal of Digital Convergence. 2013;11(1):321-7. https://doi.org/10.14400/JDPM.2013.11.11.321
  55. Bongchan Kim, Eulju Han, Youngjun Lee, Myeongjong Lee. The Statistics Study of Admission Patients to the Oriental Medical Hospital due to Traffic Accident. Journal of Korean Rehabilitation Medicine. 2001;12(4):69-78.
  56. Zhang Jie Bin. The Complete Work of Zhang Jingyue. Seoul:Yuchangdeok bookstore. 1961:896-7.
  57. Chao Yuan Fang. Treatise on the Pathogenesis and Manifestations of All Diseases. Taipei:National Medical Research Institute. 1977:24-37.
  58. Wang Qing any. Yilingaicuo. Beijing:People's Medical Publishing House. 1976:24-37.
  59. Eunji Lee, Minseok Oh, Taewon Song, Cheol-Wan Lee. Oriental Medical Treatment of Traffic Accident Aftermath. Journal of Korean Rehabilitation Medicine. 1997;7(1):218-27.
  60. Sternbach, R. A. Pain and 'hassles' in the United States: Findings of the Nuprin Pain Report. Pain. 1986;27(1):69-80. https://doi.org/10.1016/0304-3959(86)90224-1