Application of a Undaria pinnatifida for industrial cultivation of Lactobacillus

유산균의 산업적 배양을 위한 미역의 유용성 평가

  • Chang, Bo Yoon (Institute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University) ;
  • Han, Ji Hye (Institute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University) ;
  • Kim, Ju-Hee (Young Science Scharlau Korea, Jeonnam Biotechnology Research Center) ;
  • Cha, Bum-Suk (Young Science Scharlau Korea, Jeonnam Biotechnology Research Center) ;
  • Ann, Sung-Ho (Young Science Scharlau Korea, Jeonnam Biotechnology Research Center) ;
  • Kim, Sung Yeon (Institute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University)
  • 장보윤 (원광대학교 약학대학 약품연구소) ;
  • 한지혜 (원광대학교 약학대학 약품연구소) ;
  • 김주희 (영사이언스샬라우코리아) ;
  • 차범석 (영사이언스샬라우코리아) ;
  • 안성호 (영사이언스샬라우코리아) ;
  • 김성연 (원광대학교 약학대학 약품연구소)
  • Received : 2015.02.06
  • Accepted : 2015.03.30
  • Published : 2015.04.30


To optimize the medium composition of Undaria pinnatifida as a pH modulator the growth of Lactobacillus plantarum industrial scale, we analyzed the pH and growth characteristics of L. plantarum in basal medium. Subsequently, the medium compositions addition of carbon, nitrogen sources and buffering agents were optimized. When 0.5% yeast extract and 2% glucose, L. plantarum grew to maximum cell density in experimental condition. However, the growth of L. plantarum rapidly pH 4.0 in basal medium. A high alkali-ash value and low cost-effective utilization n the waste part as examined. ddition of U. pinnatifida extract alleviated the serious decrease. Among them, juice of U. pinnatifida was most helpful for the growth of L. plantarum ($36.3{\pm}1.810^8CFU/mL$). These results show that U. pinnatifida be large-scale cultivation of L. plantarum. This optimized U. pinnatifida medium can be used for safe and economical production of Lactobacillus.


Supported by : 한국산업기술진흥원, 호남지역사업평가원


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