갱년기 및 폐경 후 여성의 우울증에 대한 한방의 국외 임상연구동향 고찰

DOI QR코드

DOI QR Code

김덕호;김동일
Kim, Deok-Ho;Kim, Dong-Il

  • 투고 : 2015.04.15
  • 심사 : 2015.05.08
  • 발행 : 2015.05.29

초록

Objectives : This study were invesitigated papers published in international journals to assess the effect of Korean Medicine treatments for menopausal depression. Through this review, we aimed to research more effective ways of menopausal depression treatment. Methods : The database of this review was created through searching PubMed from Jan, 2005 to Feb, 2015 : using terms of ‘menopausal depression’ and ‘post menopausal depression’ with ‘acupuncture’, ‘alternative medicine’, ‘CAM’ and ‘herbal medicine’. Results : 119 studies were analyzed but some of them were excluded due to lack of relevance or noncomformity of subjects. Finally, 16 studies were included in this review. Conclusions : In 16 studies, the acupuncture and herb decoction had significant interventions to improve menopausal depression. Therefore Acupuncture and herbal medicine may be effective treatment method of menopausal depression.

키워드

menopausal depression;postmenopausal depression;acupuncture;herb medicine;alternative medicine;CAM

참고문헌

  1. Kessler RC, et al.. Sex and depression in the National Comorbidity Survey. I:Lifetime prevalance, chronicity and recurrence. J Affect Disord 1993;29: 85-96. https://doi.org/10.1016/0165-0327(93)90026-G
  2. Korean medicine obstetrics & gynecology textbook compilation committee. Korean medicine obstetrics & gynecology(Ⅰ). Seoul:Jeongdam. 2002:221-7.
  3. Wilmoth, MC. The middle years : women, sexuality, and the self. J Obstet Gynecol Neonatal Nurs. 1996;25(7):615-21. https://doi.org/10.1111/j.1552-6909.1996.tb02121.x
  4. Anderson E, et al. Characteristic of menopausal women seeking assistance. Am J Obstet Gynecol. 1987;156(2): 428-33. https://doi.org/10.1016/0002-9378(87)90298-5
  5. Hay AG, et al. Affective symptoms in women attending a menopause clinic. Br. J. Psychiatry. 1994;164:513-6. https://doi.org/10.1192/bjp.164.4.513
  6. Magos AL, et al. The effects of norechisterone in postmenopausal women on estrogen replacement therapy: a model for the premenstrual syndrome. British Journal of Obstetrics and Gynecology. 1986;93:1290-6. https://doi.org/10.1111/j.1471-0528.1986.tb07868.x
  7. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 3rs Rev. Ed. Washington, DC:APA. 1987.
  8. Palinkas LA, Barrett Cannor E. Estrogen use and depressive symptoms in postmenopausal women. Ob & Gy. 1992;80(1):30-6.
  9. Fishbein EG. Women at midlife: The transition to menopause. Nursing Clinics of North America. 1992;27(4):951-7.
  10. Moore AA, Noonan MD. A nurse’s Guide to hormone replacement therapy. Journal of Neonatal Nursing. 1996; 25(1):24-31. https://doi.org/10.1111/j.1552-6909.1996.tb02509.x
  11. Hamilton M. A rating scale of depression. J. Neurol. Neurosurg. Psychiatry. 1960; 23:56-62. https://doi.org/10.1136/jnnp.23.1.56
  12. Yang EY. Comparative Studies on Attitudes to the Climacteric Symptoms of Women Who have Received Hormone Replacement Therapy and Women Who have Not. Department of Nursing The Graduate School Ewha Womens University. 1996.
  13. Pitkin J, et al. Alternative and complementary therapies for the menopause. Menopause International. 2012;18:20-7.
  14. Beck A, et al. An inventory for measuring depression. Arch. Gen. psychiatry. 1961;4:561-71. https://doi.org/10.1001/archpsyc.1961.01710120031004
  15. Zung WWK. A self-rating depression scale. Arch Gen Psychiatry. 1965;12: 63-70. https://doi.org/10.1001/archpsyc.1965.01720310065008
  16. Zigmond AS, Snaith PR. The Hospital Anxiety and Depression Scale. Acta Psychiatry Scand. 1983;67:361-70. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x
  17. Greene JG. A factor analytic study of climacteric symtoms. Journal of Psychosomatic Research. 1976;20:425-30. https://doi.org/10.1016/0022-3999(76)90005-2
  18. Kupperman HS, et al. Comparative clinical evaluation estrogenic preparations by the menopausal and amenorrheal indices. J Clinic Endocrinol Metab. 1953;13:688-703. https://doi.org/10.1210/jcem-13-6-688
  19. Hauser GA. A new rating scale for climateric sndrome Menopuase Rating Scale(MRS) [in German]. Schwiz Med Wochenschr. 1997;127:122-7.
  20. Wang XY, et al. Comparative study on abdominal acupuncture and western medicine for treatment of menopause depressive disorder. Zhongguo Zhen Jiu. 2010 Nov;30(11):913-7.
  21. Painovich JM, et al. A pilot randomized, single-blind, placebo-controlled trial of traditional acupuncture for vasomotor symptoms and mechanistic pathways of menopause. Menopause. 2012 Jan; 19(1):54-61. https://doi.org/10.1097/gme.0b013e31821f9171
  22. Venzke L, et al. A randomized trial of acupuncture for vasomotor symptoms in post-menopausal women. Complement Ther Med. 2010 Apr;18(2):59-66. https://doi.org/10.1016/j.ctim.2010.02.002
  23. van Die MD, et al. Hypericum perforatum with Vitex agnus-castus in menopausal symptoms: a randomized, controlled trial. Menopause. 2009 Jan-Feb;16(1): 156-63. https://doi.org/10.1097/gme.0b013e31817fa9e0
  24. Lipovac M, et al. Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts. Maturitas. 2010 Mar;65(3):258-61. https://doi.org/10.1016/j.maturitas.2009.10.014
  25. Qu F, et al. Chinese medicinal herbs in relieving perimenopausal depression: a randomized, controlled trial. J Altern Complement Med. 2009 Jan;15(1): 93-100. https://doi.org/10.1089/acm.2008.0267
  26. Chang A, et al. The effect of herbal extract(EstroG-100) on pre-, peri- and post-menopausal women: a randomized double-blind, placebo-controlled study. Phytother Res. 2012 Apr;26(4):510-6. https://doi.org/10.1002/ptr.3597
  27. Uebelhack R, et al. Black cohoshi and St. John’s wort for climacteric complaints: a randomized trial. Obstet Gynecol. 2006 Feb;107(2 Pt 1):247-55. https://doi.org/10.1097/01.AOG.0000196504.49378.83
  28. Nappi RE, et al. Efficacy of Cimicifuga racemosa on climacteric complaints: a randomized study versus low-dose transdermal estradiol. Gynecol Endocrinol. 2005 Jan;20(1):30-5. https://doi.org/10.1080/09513590400020922
  29. Osmers R, et al. Efficacy and safety of isopropanolic black cohoshi extract for climacteric symptoms. Obstet Gynecol. 2005;105:1074-83. https://doi.org/10.1097/01.AOG.0000158865.98070.89
  30. Wuttke W, et al. The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind placebo-controlled study: effects on menopause symptoms and bone markers. Maturitas. 2003;44(Suppl 1):S67-S77. https://doi.org/10.1016/S0378-5122(02)00350-X
  31. Ushiroyama T, et al. Chai-hu-gui-zhi-gan-jiang-tang regulates plasma interleukin-6 and soluble interleukin-6 receptor concentrations and improves depressed mood in climacteric women with insomnia. Am J Chin Med. 2005; 33(5):703-11. https://doi.org/10.1142/S0192415X05003338
  32. Oliveira DS, et al. Effect of therapeutic massage on insomnia and climacteric symptoms in postmenopausal women. Climacteric. 2012 Feb;15(1):21-9. https://doi.org/10.3109/13697137.2011.587557
  33. Brooks NA, et al. Beneficial effects of Lepidium meyenii(Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content. Menopause. 2008 Nov-Dec; 15(6):1157-62. https://doi.org/10.1097/gme.0b013e3181732953
  34. Casini ML, et al. Psychological assessment of the effects of treatment with phytoestrogens on postmenopausal women: a randomized, double-blind, crossover, placebo-controlled study. Fertil Steril. 2006;85:972. https://doi.org/10.1016/j.fertnstert.2005.09.048
  35. Afonso RF, et al. Yoga decreases insomnia in postmenopausal women: a randomized clinical trial. Menopause. 2012 Feb; 19(2):186-93. https://doi.org/10.1097/gme.0b013e318228225f
  36. Katz VL, et al. Comprehensive Gynecology. Philadelphia:Mosby Elsevier. 2007.
  37. Moses EL, et al. Effects of estradiol and progesterone administration on human serotonin 2A receptor binding: A PET study. Biol Psychiatry. 2000; 48:854-60. https://doi.org/10.1016/S0006-3223(00)00967-7
  38. Hidaka T, et al. Kamishoyosan, Kampo (Japanese traditional medicine) is effective for climacteric syndrome, especially in hormone-replacement-therapy-resistant patients who strongly complain of psychological symptoms. J Obstet Gynaecol Res. 2013 Jan; 39(1):223-8. https://doi.org/10.1111/j.1447-0756.2012.01936.x
  39. Geller SE, Studee L. Botanical and dietary supplements for menopausal symptoms: what works, what does not. J Womens Health(Larchmt). 2005 Sep;14(7):634-49. https://doi.org/10.1089/jwh.2005.14.634
  40. Dog TL, Powell KL, Weisman SM. Critical evaluation of the safety of Cimicifuga racemosa in menopause symptom relief. Menopause. 2003;10: 299-313. https://doi.org/10.1097/01.GME.0000056039.51813.21
  41. Jacobson JS, Troxel AB, Evans J, et al. Randomized trial of black cohoshi for the treatment of hot flashes among women with a history of breast cancer. J Clin Oncol. 2001;19:2739-45. https://doi.org/10.1200/JCO.2001.19.10.2739
  42. Hirata JD, Swiersz LM, Zell B, Small R, Ettinger B. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril. 1997;68:981-6. https://doi.org/10.1016/S0015-0282(97)00397-X
  43. Tode T, Kikuchi Y, Hirata J, Kita T, Nakata H, Nagata I. Effect of Korean red ginseng on psychological functions in patients with severe climacteric syndromes. Int J Gynaecol Obstet. 1999;67:169-74. https://doi.org/10.1016/S0020-7292(99)00168-X
  44. Wiklund IK, Mattsson LA, Lindgren R, Limoni C. Effects of a standardized ginseng extract on quality of life and physiological parameters in symptomatic postmenopausal women: a double-blind, placebo-controlled trial. Swedish Alternative Medicine Group. Int J Clin Pharmacol Res. 1999;19:89-99.
  45. Faure ED, Chantre P, Mares P. Effects of a standardized soy extract on hot flushes: a multicenter, double-blind, randomized, placebo-controlled study. Menopause. 2002;9:329-34. https://doi.org/10.1097/00042192-200209000-00005
  46. Atkinson C, et al. The effects of phytoestrogen isoflavones on bone density in women: a double-blind, randomized, placebo-controlled trial. Am J Clin Nutr. 2004;79:326-33.
  47. Warnecke G. [Psychosomatic dysfunctions in the female climacteric. Clinical effectiveness and tolerance of Kava Extract WS 1490] Fortschr Med. 1991;109:119-22.
  48. Lucks BC. Vitex agnus castus essential oil and menopausal balance: a research update. Complement Ther Nurs Midwifery. 2003;9:157-60. https://doi.org/10.1016/S1353-6117(03)00020-9
  49. Elsabagh S, et al. Limited cognitive benefits in Stage +2 postmenopausal women after 6 weeks of treatment with Ginkgo biloba. J Psychopharmacol. 2005 Mar;19(2):173-81. https://doi.org/10.1177/0269881105049038