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Analysis of responses to physical stimuli in Caenorhabditis elegans using a microfluidic system

미세유체시스템을 이용한 예쁜꼬마선충의 물리적 자극에 대한 반응 분석

  • Published : 2015.08.31

Abstract

Caenorhabditis elegans (C.elegans) has various interesting behavioral properties, such as chemotaxis, thermotaxis, and electrotaxis. However, most previous research were only focused on single-stimulus for studying its behavioral properties. In this paper, we propose a simple and effective device for analyzing the behavior of C.elegans with combined stimuli, electric field and temperature. We compared and analyzed wild type worms (N2) and four mutant worms (tax-4, ttx-7, unc-54, unc-6). We analyzed the reaction of worms to certain stimulus and identified that this device is effective to apply a combined stimulus.

Keywords

Acknowledgement

Supported by : 한국연구재단

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