경구 처방의 경피용 제제 및 한방 화장품 소재 개발 시의 방제이론 적용에 관한 연구

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김동일;김수현;최민선;박선동
Kim, Dong-Il;Kim, Su-Hyun;Choi, Min-Sun;Park, Sun-Dong

  • 투고 : 2015.07.27
  • 심사 : 2015.08.09
  • 발행 : 2015.08.31

초록

Objectives To identify whether Sovereign-Minister-Assistant-Courier (君臣佐使) Theory and Meridian Tropism (歸經) Theory of oral herbal medicine can be applied to trans-dermal medicine and whether pharmaceutical efficacy can be delivered to skin by Courier herb (使藥). Methods We reviewed previous studies related to Sovereign-Minister-Assistant-Courier Theory. And we examined whether prescription compositions based on Sovereign-Minister-Assistant-Courier Theory correspond with efficacy results of trans-dermal medicine experimentally identified. Results When Sovereign-Minister-Assistant-Courier Theory is applied to trans-dermal medicine, Courier herb act as delivering the effective components to the lesion penetrating skin barrier. And we identified that medicine absorbed through the digestive processes may not correspond with Courier herb applied topically. Conclusions We identified that Courier herb act as delivering the effective components to the lesion. But to strength evidences, additional studies on this action will be needed.

키워드

군신좌사(君臣佐使);인경약(引經藥);사약(使藥)

참고문헌

  1. EFSA. Guidance on Dermal Absorption. EFSA journal. 2012;10(4):1-30.
  2. Kang DH, Kim HS. Functionality Analysis of Korean Medicine Fermented by Lactobacillus Strains. Korean J. Microbiol. Biotechnol. 2011;39(3):259-65.
  3. Han JH, Lee SY. Comparing Medical Efficacy of Socheongyong-tang with Lactic Acid Bacteria Fermented Socheongyong-tang. Korean J. Oriental Physiology & Pathology. 2011;25(2):246-56.
  4. Yong CS, Lee JD, Choi HG. Factors Affecting Percutaneous Absorption. the JSBR. 2000;2(1):49-68.
  5. Kim DI, et al. An empirical study on korean herbal medicine based cosmetics. Seoul:National Coordinating Center for Global Cosmetics R&D. 2015:6-8.
  6. Yang HG, et al. Ethosome Formulation for Enhanced Transdermal Delivery of Artemisia princeps Pampanini Extracts. Appl. Chem Eng. 2013;24(2):190-5.
  7. Jin EY. Modification of chemical components in herbal medicinal preparation : a case study for Artemisia and garlic. Graduate school of kyunghee university. 2014:1-39.
  8. Jung HK. Selection Criteria for Probiotics and Their Industrial Applications. Bio industry news. 2001;14:39-48.
  9. Kim HJ, et al. The Study on Investigation of Advantages and Disadvantages of Acupoint Sticking in Dog-Days and Side Effects of Acupoint Sticking in Dog-Days. J Korean Oriental Pediatrics. 2014;28(4):96-107. https://doi.org/10.7778/jpkm.2014.28.4.096
  10. Dubey V, et al. Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes. J Control Release. 2007;123(2):148-54. https://doi.org/10.1016/j.jconrel.2007.08.005
  11. Dubey V, Mishra D, Jain NK. Melatonin loaded ethanolic liposomes : physicochemical characterization and enhanced transdermal delivery. Eur J Pharm Biopharm. 2007;67(2):398-405. https://doi.org/10.1016/j.ejpb.2007.03.007
  12. Adachi T, et al. Interdigitated Structure of Phospholipid-Alcohol Systems Studied by X-Ray Diffraction. Biophysical J. 1995;68:1850-5. https://doi.org/10.1016/S0006-3495(95)80361-9
  13. Seo BI. A study on Conductant drugs in a prescription. The Korean Journal of Oriental Medical Prescription. 2001;9(1):83-103.
  14. Kim DI, et al. Analysis of Patent Information for the Development of Korea Traditional Herbal Formulation for Acne and that of Functional Cosmetics. J Korean Obstet Gynecol. 2014;27(3):104-15. https://doi.org/10.15204/jkobgy.2014.27.3.104
  15. Kim HU, et al. A systems approach to traditional oriental medicine. Nature Biotechnology. 2015;33:264-8. https://doi.org/10.1038/nbt.3167
  16. Lee YJ, Yoon CY. A Study on the Kwigyung Theory. K. O. M. S. 2007;10(1):256-67.
  17. Kim DI, et al. An empirical study on korean herbal medicine based cosmetics. Seoul:National Coordinating Center for Global Cosmetics R&D. 2014:34-61.
  18. Cosmetics Act. Korea Ministry of Goverment Legistation. available from: http://www.law.go.kr/lsInfoP.do?lsiSeq=167748&efYd=20150128#0000.
  19. Lim EM. A Study on the External Treatment of Dysmenorrhea using the Method of applying Herb-medicine at the acupoints. Journal of Korean Oriental Medicine. 1995;16(2):134-48.
  20. Kim SJ, et al. Effects of Yeosin-dan on dystocia caused by abnormal expulsive forces in Primipara. J Korean Obstet Gynecol. 2005;18(4):219-29.
  21. Kim DH, et al. Standard Principles for the Designing of Prescriptions - The Theory for Monarch, Minister, Adjuvant and Dispatcher. Korean Journal of Oriental Medical Prescription. 2003;11(2):1-18.
  22. Lee SH, Kim CY, Chang GT. Impact on Respiratory Diseases of Acupoint Sticking in Dog-Days. J Korean Oriental Pediatrics. 2012;26(2):1-12.
  23. National Coordinating Center for Global Cosmetics R&D. Planning Research of Korean Medicinal Cosmetics. 2012. Available from: www.kcii.re.kr.
  24. Kwon MS, Choi TB, Kim GY. The Effect on the Skin Barrier Function of Ceramide. Korean Journal of Aestaetics and Cosmetology. 2005;3(1):131-8.
  25. Lee JE. Drug Delivery Systems-associated with pediatric Endocrinology. J korean soc pediatr Endocrinol. 2011;16:7-12. https://doi.org/10.6065/jkspe.2011.16.1.7

피인용 문헌

  1. 1. In vitro anti-oxidant, anti-wrinkle and whitening effect of solvent fraction from takli-san vol.60, pp.3, 2017, doi:10.15204/jkobgy.2015.28.3.074