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Synthesis of 2-Amino-3-cyano-7-hydroxy-4H-chromenes Using L-Proline as a Biocatalyst

  • Behbahani, Farahnaz K. (Department of Chemistry, Karaj Branch, Islamic Azad University) ;
  • Mehraban, Sima (Department of Chemistry, Karaj Branch, Islamic Azad University)
  • Received : 2015.05.06
  • Accepted : 2015.06.04
  • Published : 2015.08.31

Abstract

Three-component one-pot synthesis of 2-amino-3-cyano-7-hydroxy-4H-chromenes, which have been reported from condensation of malononitrile, aryl aldehydes and resorcinol in the presence of L-proline under reflux conditions in ethanol.

Keywords

L-proline;Resorcinol;Chromene;Synthesis;Multicomponent reaction

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