대사증후군 환자의 치주질환과 치아상실에 관한 연구

Kang, Hyun-Joo

  • 투고 : 2015.06.15
  • 심사 : 2015.07.27
  • 발행 : 2015.08.30


본 연구는 40세 이상 중 노년 남녀의 대사증후군과 치주질환, 상실치의 관련성을 조사하여 대사증후군과 구강질환의 효과적인 관리법을 모색하고자 국민건강영양조사 제5기(2010, 2012년) 자료를 이용하여 8,225명을 최종 분석하였고, 다음과 같은 결론을 얻었다. 남자의 치주질환에 영향을 미치는 대사증후군 구성요소는 공복혈당으로 정상군에 비해서 비정상군에서 교차비가 1.27배(95% CI, 1.04~1.54) 높았다. 여자의 치주질환에 영향을 미치는 대사증후군 구성요소는 HDL 콜레스테롤, 복부비만으로 HDL 콜레스테롤이 정상군에 비해 비정상군에서 1.45배(95% CI, 1.22~1.72) 높았고, 복부비만이 정상군에 비해 비정상군에서 치주질환 교차비가 1.44배(95% CI, 1.17~1.77) 높았다. 대사증후군에 따른 치주질환 연관성은 정상군을 기준으로 위험군에서 여자의 치주질환 교차비가 1.55배(95% CI, 1.19~2.01) 높았고, 대사증후군에서 교차비가 2.25배(95% CI, 1.68~3.02) 유의하게 높았다. 여자의 상실치에 영향을 미치는 대사증후군 구성요소는 고혈압으로 혈압이 정상인 군에 비해 비정상군에서 상실치 교차비가 1.41배(95% CI, 1.10~1.82) 높았다. 여자의 대사증후군에 따른 상실치 연관성은 정상군을 기준으로 대사증후군에서 상실치 교차비가 1.48배(95% CI, 1.07~2.04)로 유의하게 높았다. 치주질환과 상실치는 대사증후군의 구성요소가 많아질수록, 위험군보다 대사증후군에서 더 영향을 받는 것으로 나타났다.


Metabolic syndrome;Missing teeth;Periodontal diseases


  1. Jang HS: The relationship between metabolic syndrome, its components, and cancer incidence in Korean. Unpublished doctoral dissertation, Ulsan University, Ulsan, 2012.
  2. Ju OJ, Jang YJ: Awareness of teachers in a region on school dental clinics and preventive programs. J Dent Hyg Sci 15: 24-31, 2015.
  3. Seong MG, Kwon HS, Moon SR, Ryu HG: Evalution of the effect of operation of toothbrushing room in between two elementary schools. J Dent Hyg Sci 15: 24-31, 2015.
  4. Ford ES, Li C: Metabolic syndrome and health-related quality of life among U.S. adults. Ann Epidemiol 18: 165-171, 2008.
  5. Grundy SM, Brewer HB, Cleeman JI, Smith SC, Lenfant C: Definition of metabolic syndrome: report of the national heart, lung and blood institute american heart association conference on scientific issues related to definition. Arterioscler Thromb Vasc Biol 24: 13-18, 2004.
  6. Primeau V, Coderre L, Karelis AD, et al.: Characterizing the profile of obese patients who are metabolically healthy. Int J Obes (Lond) 35: 971-981, 2011.
  7. Eckel RH, Grundy SM, Zimmet PZ: The metabolic syndrome. Lancet 365: 1415-1428, 2005.
  8. Cleeman JI: Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) executive summary of the third report of the national cholesterol education program (NCEP). JAMA 285: 2486-2497, 2001.
  9. Alberti KG, Zimmet P, Shaw J: Metabolic syndrome-a new world wide definition: a consensus statement from the international diabetes federation. Diabet Med 23: 469-480, 2006.
  10. Slavkin HC, Baum BJ: Relationship of dental and oral pathology to systemic illness. JAMA 284: 1215-1217, 2000.
  11. Lee S: The effect of oral health on 'health related quality of life'. Unpublished doctoral dissertation, Wonkwang University, Iksan, 2011.
  12. Choi UJ: The effects of oral health belief on the oral disease preventive activities and oral health management capacity. Unpublished doctoral dissertation, Kosin University, Busan, 2012.
  13. Carramolino-Cuellar E, Tomas I, Jimenez-Soriano Y: Relationship between the oral cavity and cardiovascular diseases and metabolic syndrome. Med Oral Patol Oral Cir Bucal 19: 289-294, 2014.
  14. Ministry of Health and Welfare: Guidebook on the 2014 integrated community health promotion plan. Ministry of Health and Welfare, Seoul, pp.9-17, 2014.
  15. Park SJ: The association of metabolic syndrome and periodontitis. Unpublished master's thesis, Chung-Ang University, Seoul, 2011.
  16. Ku IY: Comparison of oral health status by metabolic syndrome risk factors in workers. J Korea Soc Dent Hyg 13: 581-588, 2013.
  17. Grundy M, Cleeman JI, Daniels SR, et al.: Diagnosis and management of the metabolic syndrome an American Heart Association/national heart, lung, and blood institute scientific statement. Circulation 112: 2735-2752, 2005.
  18. Lee SY, Park HS, Kim SM, et al.: Cut-off points of waist circumference for defining abdominal obesity in the Korean population. Korean J Obes 15: 1-9, 2006.
  19. Jung JO. Effects of metabolic syndrome on periodontal diseases in Korean adults. J Dent Hyg Sci 12: 245-252, 2012.
  20. Nugent AP: The metabolic syndrome. Nutr Bull 29: 36-43, 2004.
  21. Lym YL, Hwang SW, Whim HJ, Oh EH, Chang YS, Cho BL: Prevalence and risk factors of the metabolic syndrome as defined by NCEP-ATP III. J Korean Acad Fam Med 24: 135-143, 2003.
  22. Kim SS: The relationship between metabolic syndrome and oral health status of Korean adults. Unpublished doctoral dissertation, Hanyang University, Seoul, 2012.
  23. Choi YH: Associations of dental disease with medical status. Unpublished doctoral dissertation, Yonsei University, Seoul, 2002.
  24. Kang HM: The association of periodontal disease, tooth loss with hypertension and diabetes. Unpublished master's thesis, Yonsei University, Seoul, 2013.
  25. Nibali L, D'Aiuto F, Griffiths G, Patel K, Suvan J, Tonetti MS: Severe periodontitis is associated with systemic inflammation and a dysmetabolic status: a case-control study. J Clin Periodontol 34: 931-937, 2007.
  26. Baek HJ, Choi YH, Lee SG, Song KB, Kwon HJ: The association of metabolic syndrome and periodontitis in Korean adult population. J Korean Aca Oral Health 34: 338-345, 2010.
  27. Shimazaki Y, Saito T, Yonemoto K, Kiyohara Y, Iida M, Yamashita Y: Relationship of metabolic syndrome to periodontal disease in Japanese women: the Hisayama study. J Dent Res 86: 271-275, 2007.
  28. Sheiham A, Watt RG: The common risk factor approach: a rational basis for promoting oral health. Community Dent Oral Epidemiol 28: 399-406, 2000.