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Pericardial mesothelioma in a dog with lymph node metastasis and chylothorax

개에서 림프절 전이와 유미흉을 동반한 심낭막 중피종 증례 보고

  • Lee, Jeong-Ha (Department of Veterinary Pathology and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Lee, Su-Hyung (Department of Veterinary Pathology and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Go, Du-Min (Department of Veterinary Pathology and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Dae-Yong (Department of Veterinary Pathology and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University)
  • 이정하 (서울대학교 수의과대학, 수의과학연구소) ;
  • 이수형 (서울대학교 수의과대학, 수의과학연구소) ;
  • 고두민 (서울대학교 수의과대학, 수의과학연구소) ;
  • 김대용 (서울대학교 수의과대학, 수의과학연구소)
  • Received : 2016.06.16
  • Accepted : 2016.11.07
  • Published : 2016.12.31

Abstract

Pericardial mesothelioma is a rare neoplasm in dogs. This report describes a case of pericardial mesothelioma in a 13-year-old Shih Tzu that presented with a clinical history of dyspnea. Hemorrhagic pericardial effusion and chylous pleural effusion with reactive mesothelial cells were identified by radiograph and cytology. Necropsy revealed multiple round nodules throughout the pericardium and regional lymph nodes in addition to chylothorax. Histopathology revealed invasive neoplasm on the pericardial surface with metastasis to the lymph nodes. The neoplastic cells were immunopositive to both cytokeratin and vimentin. Diagnosis of pericardial mesothelioma with regional lymph node metastasis was made.

Acknowledgement

Supported by : 수의과학연구소

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