대한민국 성인에서 비만과 Uric acid의 관련성

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박선영;윤현
Park, Sun Young;Yoon, Hyun

  • 투고 : 2015.11.10
  • 심사 : 2016.02.04
  • 발행 : 2016.02.29

초록

본 연구는 일부 종합검진 수검자들을 대상으로 비만수준이 혈 중 uric acid에 미치는 영향을 검토하고자 2011년 1월부터 12월까지 광주광역시의 일개 종합병원 건강검진센터에서 종합건강검진을 받았던 20세 이상의 지역주민 1,118명(남자 636, 여자 482)을 분석대상으로 하였다. 우리는 혈청 uric acid, 요소 질소, creatinine 뿐만 아니라 신체계측 (SBP, DBP 및 BMI)에 대해 평가하고, 분석에 포함 하였다. Model I에서, 연령, 성별, SBP, DBP, TC, TG, HDL-C, FBG를 보정하였을 때, 남성(p<0.001)과 여성(p=0.036)에서 uric acid의 평균값은 비만수준이 증가할수록 증가하였다. Model II에서, BUN과 creatinine을 추가로 보정하였을 때, 남성에서는 uric acid의 평균값이 정상 체중군은 $4.89{\pm}0.07mg/dl$, 과체중군은 $5.01{\pm}0.09mg/dl$, 비만군은 $5.35{\pm}0.08mg/dl$로 비만수준이 증가할수록 증가하였다(p<0.001). 그러나 여성에서는 uric acid의 평균값이 정상체중군은 $5.03{\pm}0.08mg/dl$, 과체중군은 $5.19{\pm}0.11mg/dl$, 비만군은 $5.27{\pm}0.09mg/dl$로 유의한 차이가 없었다(p=0.191). 결론적으로, 남성에서 비만수준의 증가는 혈 중 uric acid의 증가와 관련이 있지만, 여성에서는 관련이 없었다.

키워드

Obesity;BMI;Uric acid;Korean adult;Health check-up

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