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누에나방(Bombyx mori L.) 번데기 분말 섭취가 마우스의 저항성운동 훈련 후 근육량 증가에 미치는 영향

김이슬;김희빈;전병덕;이동운;류승필
Kim, Yiseul;Kim, Heebin;Jeon, Byungduk;Lee, Dong Woon;Ryu, Sungpil

  • 투고 : 2015.06.23
  • 심사 : 2015.12.03
  • 발행 : 2016.03.01

초록

식용곤충은 대체 식량자원으로 관심이 증가되고 있다. 본 연구의 목적은 누에나방 번데기 분말 섭취 유무에 따른 저항성운동 훈련(등장성 수축)이 ICR 마우스의 근육량 증가에 미치는 영향을 분석하였다. 이를 위하여 ICR 마우스 28마리를 대조군(CON), 저항성운동 훈련군(EX), 누에나방 번데기 분말 섭취군(SP), 누에나방 번데기분말 섭취 저항성운동 훈련군(SPEX)으로 그룹 당 각각 7마리씩 분류하였다. 체중증가율은 EX와 SPEX가 CON과 SP에 비해 유의하게 억제되었다. 혈중 총 단백질 농도는 SPEX가 다른 그룹에 비하여 가장 높았다. 알부민 농도 변화는 운동훈련 병행 시에만 증가하였다. 혈액 GOT와 GPT 수준은 유의차가 없었다. Akt와 Gsk-$3{\beta}$의 단백질 발현의 유의차는 없었다. 그러나 번데기 분말 섭취 시 Akt 증가 및 Gsk-$3{\beta}$의 감소 경향이 나타났다. 비복근 근육 양은 저항성 운동 훈련을 하였을 때만 증가하였다. 그리고 또한, 번데기 분말 섭취 시 근육량은 유의차가 없었으나 증가하는 경향을 보였다. 이러한 결과는 저항성 운동훈련과 누에나방 번데기 분말 섭취는 간독성을 유발하지 않고 근육량을 증가시킬 수 있다는 점을 시사한다. 그러나 보다 상세한 결과를 제시하기 위해 부가적인 연구가 필요할 것이다.

키워드

누에번데기;저항성 운동;골격근;마우스

참고문헌

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