DOI QR코드

DOI QR Code

The difference of metabolic profile between male and female zebrafish

Yoon, Dahye;Choi, Jin;Choi, Hyeonsoo;Kim, Suhkmann

  • 투고 : 2016.01.12
  • 심사 : 2016.02.19
  • 발행 : 2016.03.20

초록

Various experiments using zebrafish have been highlighted recently in the scientific community. Because it is possible to conduct practical experiment from various neurological research to area of genetic study or toxicity experiment. However, gender difference effects are nearly not considered. If the gender differences of zebrafish are considered it is possible to obtain more accurate data. In this study, zebrafish which have different genders were compared each other with NMR-based metabolomics. The extracts of male and female zebrafish were measured by 600 MHz NMR spectrometer. Statistical analysis and target profiling were conducted. As a result, muscle related metabolites were observed in male zebrafish and nerve related metabolites were observed in female zebrafish.

키워드

NMR spectroscopy;Metabolomics;Zebrafish;Pattern recognition;Target profiling

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피인용 문헌

  1. HR-MAS NMR Technique for Metabolic Profiling of Powdery Ginseng vol.20, pp.3, 2016, https://doi.org/10.6564/JKMRS.2016.20.1.013
  2. Investigation of Germicide and Growth Enhancer Effects on Bean Sprout using NMR-based Metabolomics vol.20, pp.4, 2016, https://doi.org/10.6564/JKMRS.2016.20.1.013

과제정보

연구 과제 주관 기관 : Ministry of Oceans and Fisheries