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Antihyperglycemic Effect of Water Extracts from Pleurotus cornucopiae-Containing α-Glucosidase Inhibitor

α-Glucosidase 저해물질을 함유한 노랑느타리버섯 (Pleurotus cornucopiae) 물추출물의 혈당상승 억제 효과

Shin, Ja-Won;Bae, Sang-Min;Han, Sang-Min;Lee, Yun-Hae;Jeong, Youn-Kyung;Ji, Jeong-Hyun;Lee, Jong-Soo
신자원;배상민;한상민;이윤혜;정윤경;지정현;이종수

  • Received : 2016.01.18
  • Accepted : 2016.03.09
  • Published : 2016.03.31

Abstract

Following preparation of water extracts of Pleurotus cornucopiae fruiting body-containing ${\alpha}$-glucosidase inhibitor, their antihyperglycemic effects were examined using streptozotocin-induced diabetic Sprague-Dawley (SD)-rats. The water extracts from Pleurotus cornucopiae showed dosage-dependant antihyperglycemic effects on the streptozotocin-induced diabetic SD-rats after oral administration to 120 min on the short time test and 4 days on the long time test, respectively. The water extracts from Pleurotus cornucopiae fruiting body showed dosage-dependent hypoglycemic action after administration to 120 min and 4 days in the SD-rat and streptozotocin-induced diabetic SD-rat.

Keywords

Antihyperglycemic effects;${\alpha}$-Glucosidase inhibitor;Pleurotus cornucopiae;Water extracts

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