Mouse Somatosensory Cortex Stimulation Using Pulse Modulated Transcranial Magnetic Stimulation

구형파 변조된 경두개 자기자극을 이용한 쥐의 감각피질 자극실험

Sun, Sukkyu;Seo, Taeyoon;Huh, Yeowool;Cho, Jeiwon;Kwon, Youngwoo

  • Received : 2016.02.29
  • Accepted : 2016.05.18
  • Published : 2016.06.07


In this work, a transcranial magnetic stimulation(TMS) experiment on animals is performed to stimulate the brain cortex of the mouse using modulated signals. The proposed TMS system is composed of the inverter, transformer, capacitor, variable inductor, and stimulation coil to generate 1.5 mT magnetic field in the brain cortex of the mouse. The stimulation signal is modulated to square wave where the carrier frequency is swept from 85 to 91 kHz to investigate the stimulation effect. The experimental result shows that when the carrier frequency of the stimulation signal is lower than 89 kHz, the reaction of the mouse does not change while the stimulation signal which has the carrier frequency higher than 89 kHz results in decreasing the threshold of the stimulus for the pressure.


Transcranial Magnetic Stimulation(TMS);Brain Stimulation;intermittent Theta Burst Stimulation(iTBS);Pulse Modulated Transcranial Magnetic Stimulation


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Supported by : 한국연구재단