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Relationship between the Deposition of Tear Constituents on Soft Contact Lenses according to Material and Pigmentation and Adherence of Staphylococcus aureus

소프트콘택트렌즈 재질과 착색에 따른 눈물성분 침착과 포도상구균 흡착의 상관관계

Park, So Hyun;Park, Ill-suk;Kim, So Ra;Park, Mijung
박소현;박일석;김소라;박미정

  • Received : 2016.05.09
  • Accepted : 2016.06.09
  • Published : 2016.06.30

Abstract

Purpose: The study was aimed to figure out the effect of materials and pigmentation of soft contact lens on the adherence of Staphylococcus aureus upon soft contact lenses deposited with tear components. Methods: The number of adherent S. aureus on clear and circle soft contact lenses made of etafilcon A, hilafilcon B, nelfilcon A was measured before and after incubation in artificial tear. Furthermore, the denaturalization level of tear protein with time after incubation in artificial tear was estimated by electrophoresis. Results: The adherence of S. aureus was significantly different according to the lens materials. The pattern of bacterial adherence on clear and circle contact lenses was different. That is, the adherent amount of S. aureus was somewhat larger on circle lens made of etafilcon A however, amount on circle lenses made of hilafilcon B and nelfilcon A was 89.3% and 71.3% of the number on clear lenses. When the tear protein was deposited on contact lenses, the number of adherent bacteria decreased and its degree was varied according to the lens material. The degree of decrease was the biggest in clear soft lens made of etafilcon A. Anti-bacterial effect of tear protein decreased with time after deposition of tear protein on soft contact lens and the amount of lysozyme also decreased. The reduction of anti-bacterial effect and quantity of lysozyme was different according to contact lens materials and pigmentation. Conclusions: It was revealed that the adherence of S. aureus depends on contact lens materials and pigmentation, and the specification of lens material affects more on adherence of S.aureus than pigmentation. It was further figured out the denaturalization level of anti-bacterial protein on soft contact lens varies according to lens materials and pigmentation, which produces an effect on the quantity of bacterial adherence.

Keywords

Clear soft contact lens;Circle soft contact lens;Material;Pigmentation;S. aureus;Tear protein;Lysozyme;Electrophoresis

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  2. Changes in Subjective/Objective Symptoms and Lens Parameters by the Education for Cosmetic Contact Lens Care vol.21, pp.4, 2016, https://doi.org/10.14479/jkoos.2016.21.4.361
  3. The Stability and Safety Evaluations of Soft Contact Lenses past their Expiry Date vol.22, pp.1, 2017, https://doi.org/10.14479/jkoos.2017.22.1.33
  4. Correlation between Tear Proteins Deposition and Oxygen Transmissibility of Soft Contact Lenses vol.22, pp.2, 2017, https://doi.org/10.14479/jkoos.2017.22.2.97
  5. Biofilm Formation and its Related Gene Expression in Staphylococcus aureus on Different Materials of Soft Contact Lenses vol.22, pp.3, 2017, https://doi.org/10.14479/jkoos.2017.22.3.205

Acknowledgement

Supported by : 서울과학기술대학교