Angina Bullosa Hemorrhagica: A Case Report

  • Park, Jun-Hyong ;
  • Yoon, Jung-Hoon ;
  • Kang, Jin-Kyu
  • Received : 2016.05.20
  • Accepted : 2016.05.28
  • Published : 2016.06.30


Angina bullosa hemorrhagica (ABH) is a rare oral mucosal disorder characterized by blood blisters which is not related to hematologic or immunopathologic abnormalities. ABH is most common in middle-aged and elderly people and associated with local trauma, diabetes and long-term use of inhaled steroids. Diagnosis is generally based on reviewing history and clinical presentation and it is important to distinguish it from other serious disorders. Usually, ABH is benign condition which requires no treatment. We present a case of 81-year-old female with ABH.


Angina bullosa hemorrhagica;Blood blister;Oral mucosa


  1. Deblauwe BM, van der Waal I. Blood blisters of the oral mucosa (angina bullosa haemorrhagica). J Am Acad Dermatol 1994;31:341-344.
  2. Neville BW, Damm DD, Allen CM, Chi AC. Oral and maxillofacial pathology. 4th ed. St. Louis: Elsevier; 2015. pp. 774.
  3. Horie N, Kawano R, Inaba J, et al. Angina bullosa hemorrhagica of the soft palate: a clinical study of 16 cases. J Oral Sci 2008;50:33-36.
  4. Stephenson P, Lamey PJ, Scully C, Prime SS. Angina bullosa haemorrhagica: clinical and laboratory features in 30 patients. Oral Surg Oral Med Oral Pathol 1987;63:560-565.
  5. Beguerie JR, Gonzalez S. Angina bullosa hemorrhagica: report of 11 cases. Dermatol Reports 2014;6:5282.
  6. Luthra K, Reddy Y, Wadhawan R, Solanki G. Angina bullosa hemorrhagica; a rare entity: an overview. Acta Biomedica Scientia 2014;1:133-135.
  7. Shashikumar B, Reddy RR, Harish M. Oral hemorrhagic blister: an enigma. Indian J Dermatol 2013;58:407.
  8. Grinspan D, Abulafia J, Lanfranchi H. Angina bullosa hemorrhagica. Int J Dermatol 1999;38:525-528.
  9. Martins CAM, Gomes FV, Freddo AL, Heitz C, Moresco FC, da Silveira JOL. Angina bullosa haemorrhagica (ABH): diagnosis and treatment. RFO UPF 2012;17:347-351.
  10. Pahl C, Yarrow S, Steventon N, Saeed NR, Dyar O. Angina bullosa haemorrhagica presenting as acute upper airway obstruction. Br J Anaesth 2004;92:283-286.
  11. Hopkins R, Walker DM. Oral blood blisters: angina bullosa haemorrhagica. Br J Oral Maxillofac Surg 1985;23:9-16.
  12. Giuliani M, Favia GF, Lajolo C, Miani CM. Angina bullosa haemorrhagica: presentation of eight new cases and a review of the literature. Oral Dis 2002;8:54-58.
  13. Prakash SMR, Toshniwal OPD, Singh NN, Verma S. Angina bullosa hemorrhagica with a possible relation to dental treatment, diabetes mellitus, steroid inhaler and local trauma: report of 3 cases. J Indian Acad Oral Med Radiol 2010;22(Suppl):S42-S44.
  14. Patigaroo SA, Dar NH, Thinles T, ul Islam M. Multiple angina bullosa hemorrhagica: a case report. Int J Pediatr Otorhinolaryngol Extra 2014;9:125-127.
  15. Edwards S, Wilkinson JD, Wojnarowska F. Angina bullosa haemorrhagica--a report of three cases and review of the literature. Clin Exp Dermatol 1990;15:422-424.
  16. Martini MZ, Lemos CA Jr, Shinohara EH. Angina bullosa hemorrhagica: report of 4 cases. Minerva Stomatol 2010;59:139-142.
  17. da Rosa AM, Pappen FG, Gomes APN. Angina bullosa hemorrhagica: a rare condition? RSBO (Online) 2012;9:190-192.
  18. Rai S, Kaur M, Goel S. Angina bullosa hemorrhagica: report of two cases. Indian J Dermatol 2012;57:503.


Supported by : Wonkwang University