The Study on Signal to Noise Ratio of Single-Shot Turbo Spin Echo to Reduce Image Distortion in Brain Stem Diffusion MRI

뇌줄기 확산강조 자기공명영상검사 시 뒤틀림을 줄이기 위한 SS-TSE 기법의 신호대잡음비 연구

Koo, Nohyun;Lee, Hobeom;Choi, Kwanwoo;Son, Soonyong;Yoo, Beonggyu

  • Received : 2016.05.18
  • Accepted : 2016.06.30
  • Published : 2016.06.30


The purpose of this study was to investigate the problems of low signal-to-noise ratio(SNR) of single-shot turbo spin echo(SS-TSE) by quantifying numerically decreased signal to noise ratio. Thirty five patients without brain disease underwent diffusion MRI in 3T scanner from July to October in 2015. Single shot echo planar imaging(SS-EPI) which is conventionally used in MRI was taken to compared SS-TSE in SNR of medulla oblongata. As a result, SNR of SS-TSE diffusion(b0=$314.41{\pm}42.96$, b1000=$117.33{\pm}14.04$) is than SS-EPI diffusion(b0=$514.84{\pm}48.97$, b=$208.65{\pm}25.70$) lower in b=0 image(38.9%) and b=1,000 image(43.8%). Thus, diffusion MR using SS-EPI of MS-EPI should be taken for diagnosis of disease in brain stem due to decreased SNR of diffusion using SS-TSE.


Diffusion weighted image;Single-shot turbo spin echo(SS-TSE);Single-shot echo planar imaging(SS-EPI);Signal to noise ratio;Brain stem


  1. C. Z. Simonsen, M. H. Madsen, M. L. Schmitz, I. K. Mikkelsen, M. Fisher, G. Andersen, "Sensitivity of diffusion- and perfusion-weighted imaging for diagnosing acute ischemic stroke is 97.5%", Stroke, Vol. 45, No. 1, pp. 98-101, 2015.
  2. J. H. Lee, Y. S. Yu, J. S. Lee, I. C. Im, Application of the Orally Inserted Guiding Device for the Improved Motion Artifacts of the Cervical Spine MRI", Journal of the Korean Society of Radiology, Vol. 8, No. 6, 2014.
  3. Y. L. Thian, W. Xie, D. A. Porter, A. B. Weileng, "Readout-segmented echo-planar imaging for diffusion-weighted imaging in the pelvis at 3T-A feasibility study", Academic Radiology, Vol. 21, No. 4, pp. 531-537, 2014.
  4. S. J. Holdsworth, M. U. Antonucci, J. B. Andre, J. Rosenberg, M. Aksoy, M. Straka, N. J. Fischbein, R. Bammer, M. E. Moseley, G. Zaharchuk, S. Skare, "Diffusion-weighted imaging with dual-echo echo-planar imaging for better sensitivity to acute stroke", American Journal of Neuroradiology, Vol. 35, No. 7, pp. 1293-1302, 2014.
  5. K. W. Yeom, S. J. Holdsworth, A. T. Van, R. M. Lober, R. Bamme, "Comparison of readout-segmented echo-planar imaging (EPI) and single-shot EPI in clinical application of diffusion-weighted imaging of the pediatric brain" American Journal of Roentgenology, Vol. 200, No. 5, pp. 437-443, 2013.
  6. K. P. Pruessmann, M. Weiger, M. B. Scheidegger, P. Boesiger, "SENSE: sensitivity encoding for fast MRI", Magnetic Resonance in Medicine, Vol. 42, No. 5, pp. 952-962, 1999.<952::AID-MRM16>3.0.CO;2-S
  7. H. Tokoro, Y. Fujinaga, A. Ohya, K. Ueda, A. Shiobara, Y. Kitou, H. Ueda, M. Kadoya, "Usefulness of free-breathing readout-segmented echo-planar imaging (RESOLVE) for detection of malignant liver tumors: comparison with single-shot echo-planar imaging (SS-EPI)", European Journal of Radiology, Vol. 83, No. 10, pp. 1728-1733, 2014.
  8. B. D. Foer, J. P. Vercruysse, B. Pilet, J. Michiels, R. Vertriest, M. Pouillon, T. Somers, J. W. Casselman, E. Offeciers, "Single-shot, turbo spin-echo, diffusion- weighted imaging versus spin-echo-planar, diffusion- weighted imaging in the detection of acquired middle ear cholesteatoma", American Journal of Neuroradiology, Vol. 27, No. 7, pp. 1480-1482, 2006.
  9. R. Bammer, "Basic principles of diffusion-weighted imaging", European Journal of Radiology, Vol. 45, No. 3, pp. 169-184, 2003.
  10. K. O. Lovblad, P. M. Jakob, Q. Chen, A. E. Baird, G. Schlaug, S. Warach, R. R. Edelman, "Turbo spin-echo diffusion-weighted MR of ischemic stroke", American Journal of Neuroradiology, Vol. 19, No. 2, pp. 201-208, 1998.
  11. International Atomic Energy Agency, Available from:, accessed Feb, 10, 2016.
  12. A. J. McCann, A. Workman, C. McGrath, "A quick and robust method for measurement of signal-to-noise ratio in MRI", Physics in Medicine and Biology, Vol. 58, No. 7, pp. 3775-3790, 2013.
  13. P. D. Graaf, P. J. Pouwels, F. Rodjan, A. C. Moll, S. M. Imhof, D. L. Knol, E. Sanchez, J. A. Castelijns, "Single-shot turbo spin-echo diffusion- weighted imaging for retinoblastoma: initial experience", American Journal of Neuroradiology, Vol. 33, No. 1, pp. 110-118, 2012.
  14. M. H. Verhappen, P. J. Pouwels, R. L. jumanovic, D. L. Knol, R. De Bree, J. A. Castelijns, "Diffusion-weighted MR imaging in head and neck cancer: comparison between half-fourier acquired single-shot turbo spin-echo and EPI techniques", American Journal of Neuroradiology, Vol. 33 No. 7, pp. 1239-1246, 2012.


Supported by : 원광보건대학교