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The anti-histamine effect of water soluble alkaloids extracted from solanum nigrum L.

용규에서 추출된 수용성 알칼로이드성분의 항히스타민 효과

  • Received : 2016.05.03
  • Accepted : 2016.08.24
  • Published : 2016.08.25

Abstract

The whole herbs of solanum nigrum L were extracted in boiling water (SNL-W), and the extracts were separated with butyl alcohol fraction (SNL-W/B) and aqueous fraction (SNL-W/W) by the solvent extraction method. The total alkaloid and total saponin content mensuration were used to identify the alkaloid composition of methanol fraction extracted from the aqueous fraction. The venom of honey bee was used to induce the rat peritoneal mast cell to secreting the histamine. The results show that the water soluble alkaloid composition of solanum nigrum L (SNL-W/W/M) has a significant inhibitory effect on the histamine release.

Keywords

solanum nigrum L;alkaloid;histamine;honey bee venom

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