- Volume 46 Issue 1
DOI QR Code
Inhibitory Effects of Myelophycus simplex Papenfuss Methanol Extract on Melanogenesis in B16F10 Melanoma Cells
바위수염 메탄올 추출물이 B16F10 흑색종 세포에서의 멜라닌합성에 미치는 영향
- Kim, Hyang Suk (Anti-aging Research Center, Dong-Eui University) ;
- Cheon, Ji Min (Department of Food and Nutrition, Dong-Eui University) ;
- Kwon, Da Hye (Anti-aging Research Center, Dong-Eui University) ;
- Choi, Eun Ok (Anti-aging Research Center, Dong-Eui University) ;
- Kim, Min Ju (Lioele Cosmetic Co., Ltd.) ;
- Choi, Yung Hyun (Department of Oriental Medicine, Dong-Eui University) ;
- Kim, Byung Woo (Department of Life Science and Biotechnology, Dong-Eui University) ;
- Hwang, Hye Jin (Department of Food and Nutrition, Dong-Eui University)
- 김향숙 (동의대학교 항노화연구소) ;
- 천지민 (동의대학교 식품영양학과) ;
- 권다혜 (동의대학교 항노화연구소) ;
- 최은옥 (동의대학교 항노화연구소) ;
- 김민주 ((주)리오엘리) ;
- 최영현 (동의대학교 한의학과) ;
- 김병우 (동의대학교 생명응용학과) ;
- 황혜진 (동의대학교 식품영양학과)
- Received : 2016.11.09
- Accepted : 2017.01.10
- Published : 2017.01.31
Myelophycus simplex Papenfuss, a type of brown algae, is known to be majorly distributed in along the southern coast of Korea and Japan. The purpose of this study was to investigate the effects of M. simplex Papenfuss methanol extract (MSPME) on melanogenesis in
Supported by : 동의대학교 블 루바이오 소재 개발 및 실용화 지원 센터
- Hill HZ, Li W, Xin P, Mitchell DL. 1997. Melanin: a two edged sword?. Pigment Cell Res 10: 158-161. https://doi.org/10.1111/j.1600-0749.1997.tb00478.x
- Buscà R, Ballotti R. 2000. Cyclic AMP a key messenger in the regulation of skin pigmentation. Pigment Cell Res 13: 60-69. https://doi.org/10.1034/j.1600-0749.2000.130203.x
- Kreiner PW, Gold CJ, Keirns JJ, Brock WA, Bitensky MW. 1973. Hormonal control of melanocytes: MSH-sensitive adenyl cyclase in the Cloudman melanoma. Yale J Biol Med 46: 583-591.
- Tada A, Suzuki I, Im S, Davis MB, Cornelius J, Babcock G, Nordlund JJ, Abdel-Malek ZA. 1998. Endothelin-1 is a paracrine growth factor that modulates melanogenesis of human melanocytes and participates in their responses to ultraviolet radiation. Cell Growth Differ 9: 575-584.
- Costin GE, Hearing VJ. 2007. Human skin pigmentation: melanocytes modulate skin color in response to stress. FASEB J 21: 976-994. https://doi.org/10.1096/fj.06-6649rev
- Prota G. 1990. Recent advances in the chemistry of melanogenesis in mammals. J Invest Dermatol 75: 122-127.
- Pavel S, Muskiet FA. 1980. Eumelanin (precursor) metabolites as markers for pigmented malignant melanoma: a preliminary report. Cancer Detect Prev 6: 311-316.
- Choi EO, Kim HS, Han MH, Choi YH, Park C, Kim BW, Hwang HJ. 2013. Effect of Hizikia fusiforme fractions on melanin synthesis in B16F10 melanoma cells. J Life Sci 23: 1495-1500. https://doi.org/10.5352/JLS.2013.23.12.1495
- Cho EK, Choi YJ. 2010. Physiological activities of hot water extracts from Ecklonia cava Kjellman. J Life Sci 20: 1675-1682. https://doi.org/10.5352/JLS.2010.20.11.1675
- Chan YY, Kim KH, Cheah SH. 2011. Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells. J Ethnopharmacol 137: 1183-1188. https://doi.org/10.1016/j.jep.2011.07.050
- Kim DM, Kim KH, Sung NY, Jung PM, Kim JS, Kim JK, Kim JH, Choi J, Song BS, Lee JW, Kim JK, Yook HS. 2011. Effect of gamma irradiation on the extraction yield and whitening activity of polysaccharides from Undaria pinnatifida sporophyll. J Korean Soc Food Sci Nutr 40: 712-716. https://doi.org/10.3746/jkfn.2011.40.5.712
- Noda H, Amano H, Arshima K, Hashimoto S, Nisizawa K. 1989. Studies on the antitumor activity of marine algae. Nippon Suisan Gakkaishi 55: 1259-1264. https://doi.org/10.2331/suisan.55.1259
- Schwartsmann G, Brondani da Rocha A, Berlinck RG, Jimeno J. 2001. Marine organisms as a source of new anticancer agents. Lancet Oncol 2: 221-225. https://doi.org/10.1016/S1470-2045(00)00292-8
- Kwon DJ, Lim ST, Chung YJ, Park SH, Kweon DK. 2006. Comprehension and practical use of fucoidan extracted from brown sea weeds. Food Sci Ind 39: 73-80.
- Oh BG, Lee JW, Lee HB. 2002. A summer marine benthic algal flora and community of uninhabited islands in Haenamgun, southern coast of Korea. J Korean Fish Soc 35: 57-63.
- Shin DB, Han EH, Park SS. 2014. Cytoprotective effects of phaeophyta extracts from the coast of Jeju island in HT-22 mouse neuronal cells. J Korean Soc Food Sci Nutr 43: 224-230. https://doi.org/10.3746/jkfn.2014.43.2.224
- Kim HS, Kwon DH, Choi EO, Kim JH, Han MH, Choi YH, Kim BW, Hwang HJ. 2015. Effects of Myelophycus simplex Papenfuss methanol extract on adipocyte differentiation and adipogenesis in 3T3-L1 preadipocytes. J Life Sci 25: 62-67. https://doi.org/10.5352/JLS.2015.25.1.62
Friedmann PS, Wren F, Buffey J, Macneil S. 1990.
$\alpha$-MSH causes a small rise in cAMP but has no effect on basal or ultraviolet-stimulated melanogenesis in human melanocytes. Br J Dermatol 123: 145-151. https://doi.org/10.1111/j.1365-2133.1990.tb01841.x
Hunt G, Todd C, Cresswell JE, Thody AJ. 1994.
$\alpha$-Melanocyte stimulating hormone and its analogue Nle4DPhe7 $\alpha$- MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes. J Cell Sci 107: 205-211.
- Kim JW, Kim DK, Park JS, Lee YK, Beik KY, Kim SD. 2009. Antioxidant and antimicrobial activities of shark collagens, and inhibitory actions on elastase and tyrosinase. Korena J Food Preserv 16: 419-426.
- Jung SH, Ku MJ, Moon HJ, Yu BC, Jeon MJ, Lee YH. 2009. Inhibitory effects of fucoidan on melanin synthesis and tyrosinase activity. J Life Sci 19: 75-80. https://doi.org/10.5352/JLS.2009.19.1.075