Effect of Gd-EOB-DTPA on Hepatic Fat Quantification using Two-point Dixon Technique

Two-point Dixon기법을 이용한 간의 지방정량화에 Gd-EOB-DTPA가 미치는 영향

  • 구노현 (서울아산병원 영상의학과) ;
  • 최관우 (서울아산병원 영상의학과) ;
  • 유병규 (원광보건대학교 방사선과)
  • Received : 2017.04.04
  • Accepted : 2017.05.04
  • Published : 2017.07.28


The purpose of present study was to assess whether Gd-EOB-DTPA with gadolinium-based contrast agent administration affects fat quantification using the two-point Dixon technique. Between April 2016 and September, 60 patients who underwent hepatic fat quantification using the two-point Dixon technique were divided into two group (normal liver donors=30, abnormal hepatic steatosis=30) and we compared the variability of mean fat fraction before and after administration Gd-EOB-DTPA. As a results, in both group, fat fraction after injection Gd-EOB-DTPA was significantly decreased (normal liver donors -33.8%, hepatic steatosis -47.2%) compared to before injection Gd-EOB-DTPA, suggesting that Gd-EOB-DTPA affects fat quatification using two-point Dixon technique. In conclusion, hepatic fat quantification using the two-point Dixon technique could maintain diagnostic value by acquiring images before administration Gd-EOB-DTPA.


Supported by : 원광보건대학교


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