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Research Trends in Photothermal Therapy Using Gold Nanoparticles

금 나노입자를 이용한 광열치료 연구 동향

  • Kim, Bong-Geun (Department of Chemical Engineering, Myongji University) ;
  • Yeo, Do Gyeong (Department of Chemical Engineering, Myongji University) ;
  • Na, Hyon Bin (Department of Chemical Engineering, Myongji University)
  • 김봉근 (명지대학교 화학공학과) ;
  • 여도경 (명지대학교 화학공학과) ;
  • 나현빈 (명지대학교 화학공학과)
  • Received : 2017.05.02
  • Accepted : 2017.07.05
  • Published : 2017.08.10

Abstract

The photothermal therapy is a method of cell ablation using the heat converted from the incident light by photothermal transducers. It offers a selective treatment to desired abnormal cells, in particular, tumor tissues. Among various photothermal agents, gold nanoparticles (Au NPs) have received enormous attention due to their unique physicochemical property over last two decades. In this review, we address research strategies and methods to improve treatment efficacy by organizing recent research works. We mainly focus on research works to enhance light-to-heat conversion via optimizing the morphology of Au NPs and related assemblies as well as the strategies to deliver Au NPs efficiently to specific targets. We also introduce convergence research efforts to combine Au NP-mediated photothermal treatment and other functions such as diagnostic capabilities and other therapeutic methods.

Acknowledgement

Supported by : 명지대학교

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