Inhibitory activities of phenolic compounds isolated from Chionanthus retusa flower on biological enzymes

이팝나무 꽃에서 분리한 페놀 화합물의 생리활성 효소 억제효과

  • Lee, Eun-Ho (School of Food Science and Biotechnology/Food and Bio-Industry Research Institute, Kyungpook National University) ;
  • Cho, Young-Je (School of Food Science and Biotechnology/Food and Bio-Industry Research Institute, Kyungpook National University)
  • 이은호 (경북대학교 식품공학부/식품생물산업연구소) ;
  • 조영제 (경북대학교 식품공학부/식품생물산업연구소)
  • Received : 2017.12.18
  • Accepted : 2018.02.20
  • Published : 2018.02.28


This study was designed to determine the biological activities of Chionanthus retusus flower extracts. Water and 90% ethanol extracts of C. retusus flower were prepared. The inhibitory activities of water and ethanol extracts with a phenolic content of $200{\mu}g/mL$ against xanthine oxidase were 25.60% and 15.92%, respectively. Further, the water extract did not show any inhibitory activity against ${\alpha}$-glucosidase whereas the ethanol extract showed 100.00% inhibition of ${\alpha}$-glucosidase. The inhibitory activities of the extracts against tyrosinase were 17.27% (water extract) and 36.13% (ethanol extract), which suggest that the extracts may have a whitening effect. The water extract did not inhibit elastase activity but showed a collagenase-inhibitory activity of 20.21%. On the contrary, the ethanol extract showed 96.26% and 35.93% inhibition of collagenase and elastase, respectively. These findings suggest that the extracts may have an anti-wrinkle effect. Lastly, the extracts showed a hyaluronidase inhibitory activity of 36.96% (water extract) and 88.70% (ethanol extract), suggesting that they may have an anti-inflammatory effect. The results indicate that C. retusus flower extracts containing phenolic compounds can be used as functional resources because they have anti-gout, carbohydrate degradation-inhibitory, whitening, anti-wrinkle, and anti-inflammatory effects.


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