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Antioxidant, antibacterial, antifungal, and anti-inflammatory effects of 15 tree essential oils

수목 방향유 15종의 산화방지, 항세균, 항진균 및 항염증 효과

  • Jo, Se Jin (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Park, Mi-Jin (Division of Wood chemistry, Department of Forest products, National Institute of Forest Science) ;
  • Guo, Rui Hong (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Park, Jung Up (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Yang, Ji Yoon (Division of Wood chemistry, Department of Forest products, National Institute of Forest Science) ;
  • Kim, Jae-Woo (Division of Wood chemistry, Department of Forest products, National Institute of Forest Science) ;
  • Lee, Sung-Suk (Division of Wood chemistry, Department of Forest products, National Institute of Forest Science) ;
  • Kim, Young Ran (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
  • 조세진 (전남대학교 약학대학) ;
  • 박미진 (국립산림과학원 목재이용연구부 목재화학연구과) ;
  • 궈루이홍 (전남대학교 약학대학) ;
  • 박정업 (전남대학교 약학대학) ;
  • 양지윤 (국립산림과학원 목재이용연구부 목재화학연구과) ;
  • 김재우 (국립산림과학원 목재이용연구부 목재화학연구과) ;
  • 이성숙 (국립산림과학원 목재이용연구부 목재화학연구과) ;
  • 김영란 (전남대학교 약학대학)
  • Received : 2018.07.26
  • Accepted : 2018.09.26
  • Published : 2018.10.31

Abstract

The current study investigated the beneficial effects of 15 essential oils isolated from tree branches, leaves, and flowers. Among these oils, clove bud and Illicium anisatum oils showed the most potent anti-oxidant effects on 1,1-diphenyl-2-picrylhydrazyl and 2,2'azinbis-(3-ethyl-benzothiazoline-6-sulfonic acid) radical scavenging activities. Next, we evaluated the antibacterial effects of 15 essential oils on Staphylococcus aureus, Listeria monocytogenes, Escherichia coli O157:H7, Salmonella typhimurium, and Streptococcus mutans. Clove bud significantly decreased growth of 5 bacterial strains. In addition, clove bud, Magnolia kobus, Picea abies and Chamaecyparis obtuse significantly reduced growth of the fungi, Aspergillus fumigatus, Aspergillus ochraceus, Candida albicans and Trichophyton rubrum. Additionally, clove bud also remarkably reduced the expression of cyclooxygenase-2 and inducible NO synthase in lipopolysaccharide-activated RAW264.7 cells. These results indicate that essential oils isolated from trees, which exhibit antioxidant, antibacterial, antifungal and anti-inflammatory properties, may be potentially useful in the development of cosmetic ingredients.

Acknowledgement

Supported by : 국립산림과학원

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