Oculogyric Crisis Due to Metronidazole Toxic Encephalopathy

메트로니다졸 독성 뇌병증으로 인한 안구운동발작

  • Lee, Sang-Woo (Department of Neurology, Soonchunhyang University Bucheon Hospital) ;
  • Kim, Hyeongseok (Department of Neurology, Soonchunhyang University Bucheon Hospital) ;
  • Heo, Deokhyun (Department of Neurology, Soonchunhyang University Bucheon Hospital) ;
  • Park, Jeong-Ho (Department of Neurology, Soonchunhyang University Bucheon Hospital)
  • 이상우 (순천향대학교 부천병원 신경과) ;
  • 김형석 (순천향대학교 부천병원 신경과) ;
  • 허덕현 (순천향대학교 부천병원 신경과) ;
  • 박정호 (순천향대학교 부천병원 신경과)
  • Received : 2018.04.30
  • Accepted : 2018.06.19
  • Published : 2018.11.30


Oculogyric crisis is an acute dystonia involving ocular muscles characterized by sustained conjugate upward or lateral deviation of the eyes. Metronidazole is a commonly used antimicrobial agent in treatment of anaerobic infections. However, its long-term use can cause toxic encephalopathy particularly in patients with hepatic dysfunction. Here, we describe a case of oculogyric crisis as a presenting manifestation of metronidazole-induced encephalopathy.



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