- Volume 59 Issue 4
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Severe pulmonary mineralization in a dog with pituitary-dependent hyperadrenocorticism: a case report
- Yoon, Ji-Seon (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonbuk National University) ;
- Kang, Seongwoo (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
- Park, Jinho (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonbuk National University) ;
- Choi, Jihye (Department of Veterinary Diagnostic Imaging, College of Veterinary Medicine, Chonnam National University) ;
- Yu, DoHyeon (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Gyeongsang National University)
- 투고 : 2019.05.25
- 심사 : 2019.10.29
- 발행 : 2019.12.31
A 7-year-old, spayed female Chihuahua with dyspnea, intermittent cyanosis, and dermal plaques was diagnosed with hyperadrenocorticism. Thoracic radiographs showed markedly hyperdense alveoli in multiple lung lobes. Computed tomography (CT) images showed lung mineralization confined to the lung parenchyma and pituitary macroadenoma. Pulmonary mineralization secondary to hyperadrenocorticism is commonly found on histopathologic examination. However, those lesions are rarely identified radiographically. We describe obvious pulmonary mineralization secondary to hyperadrenocorticism found on radiographs and present the first report regarding CT imaging of the mineralization. Pulmonary mineralization should be considered when a dog affected by hyperadrenocorticism shows diffuse lung mineralization on radiographs.
연구 과제 주관 기관 : National Research Foundation of Korea (NRF)
- Chan ED, Morales DV, Welsh CH, McDermott MT, Schwarz MI. Calcium deposition with or without bone formation in the lung. Am J Respir Crit Care Med 2002;165:1654-1669. https://doi.org/10.1164/rccm.2108054
- Huntley K, Frazer J, Gibbs C, Gaskell CJ. The radiological features of canine Cushing's syndrome: a review of fortyeight cases. J Small Anim Pract 1982;23:369-380. https://doi.org/10.1111/j.1748-5827.1982.tb02071.x
- Marsh S, Aldington S, Williams MV, Nowitz MR, Kingzett-Taylor A, Weatherall M, Shirtcliffe PM, McNaughton AA, Pritchard A, Beasley R. Utility of lung density measurements in the diagnosis of emphysema. Respir Med 2007;101:1512-1520. https://doi.org/10.1016/j.rmed.2007.01.002
- Berry CR, Hawkins EC, Hurley KJ, Monce K. Frequency of pulmonary mineralization and hypoxemia in 21 dogs with pituitary-dependent hyperadrenocorticism. J Vet Intern Med 2000;14:151-156. https://doi.org/10.1111/j.1939-1676.2000.tb02229.x
- Blois SL, Caron I, Mitchell C. Diagnosis and outcome of a dog with iatrogenic hyperadrenocorticism and secondary pulmonary mineralization. Can Vet J 2009;50:397-400.
- Chung MJ, Lee KS, Franquet T, Muller NL, Han J, Kwon OJ. Metabolic lung disease: imaging and histopathologic findings. Eur J Radiol 2005;54:233-245. https://doi.org/10.1016/j.ejrad.2004.07.003
- Belem LC, Zanetti G, Souza AS Jr, Hochhegger B, Guimaraes MD, Nobre LF, Rodrigues RS, Marchiori E. Metastatic pulmonary calcification: state-of-the-art review focused on imaging findings. Respir Med 2014;108:668-676. https://doi.org/10.1016/j.rmed.2014.01.012
- Widmer WR, Guptill L. Imaging techniques for facilitating diagnosis of hyperadrenocorticism in dogs and cats. J Am Vet Med Assoc 1995;206:1857-1864.
- Kemerink GJ, Kruize HH, Lamers RJ, van Engelshoven JM. Density resolution in quantitative computed tomography of foam and lung. Med Phys 1996;23:1697-1708. https://doi.org/10.1118/1.597757