Aspergillus fumigatus infection in an ostrich with an enlarged neck due to respiratory problems

  • Woo, Gye-Hyeong (Laboratory of Histopathology, Department of Clinical Laboratory Science, Semyung University)
  • Received : 2019.09.18
  • Accepted : 2019.11.05
  • Published : 2019.12.31


This study describes a sudden death in an ostrich (Struthio camelus) with a big neck. Grossly, the air sacs were thickened. Yellow to white, round or coalescent material was scattered on the air sacs. However, the cervical air sac was normal. Histopathologically, multinucleated giant cells, heterophils, and macrophages had infiltrated the air sacs, and many hyphae were seen in the air sacs and on their surfaces. Pyogranulomatous inflammation with intralesional hyphae was observed throughout the lungs. Aspergillus fumigatus was identified microbiologically. In conclusion, the affected animal died because of the respiratory disturbance caused by mycotic airsacculitis and pneumonia.


Supported by : Semyung University


  1. Bennett JW. An overview of the genus Aspergillus. In: Machida M, Gomi K (eds). Aspergillus: Molecular Biology and Genomics. pp. 1-17, Caister Academic Press, Norfolk, 2010.
  2. Fischer D, Van Waeyenberghe L, Failing K, Martel A, Lierz M. Single tracheal inoculation of Aspergillus fumigatus conidia induced aspergillosis in juvenile falcons (Falco spp.). Avian Pathol 2018;47:33-46.
  3. Nemeth NM, Gonzalez-Astudillo V, Oesterle PT, Howerth EW. A 5-year retrospective review of avian diseases diagnosed at the department of pathology, University of Georgia. J Comp Pathol 2016;155:105-120.
  4. Sabino R, Burco J, Valente J, Verissimo C, Clemons KV, Stevens DA, Tell LA. Molecular identification of clinical and environmental avian Aspergillus isolates. Arch Microbiol 2019;201:253-257.
  5. Seyedmousavi S, Guillot J, Arn P, de Hoog GS, Mouton JW, Melchers WJ, Verweij PE. Aspergillus and aspergilloses in wild and domestic animals: a global health concern with parallels to human disease. Med Mycol 2015;53:765-797.
  6. Charlton BR, Chin RP, Barnes HJ. Fungal infections. In: Swayne DE, Glisson JR, McDougald LR, Nolan LK, Suarez DL, Nair VL (eds.). Diseases of Poultry. 13th ed. pp. 1077-1096, John Wiley & Sons Inc., Ames, 2013.
  7. Fitzgerald SD, Moisan PG. Mycotic rhinitis in an ostrich. Avian Dis 1995;39:194-196.
  8. Khosravi AR, Shokri H, Ziglari T, Naeini AR, Mousavi Z, Hashemi H. Outbreak of severe disseminated aspergillosis in a flock of ostrich (Struthio camelus). Mycoses 2008;51:557-559.
  9. Yokota T, Shibahara T, Wada Y, Hiraki R, Ishikawa Y, Kadota K. Aspergillus fumigatus infection in an ostrich (Struthio camelus). J Vet Med Sci 2004;66:201-204.
  10. Rousseaux CG, Dalziel JB. Aspergillus pneumonia in an ostrich (Struthio camelus). Aust Vet J 1981;57:151-152.
  11. Perelman B, Kuttin ES. Aspergillosis in ostriches. Avian Pathol 1992;21:159-163.
  12. Perez J, Garcia PM, Mendez A, Astorga R, Luque I, Tarradas C. Outbreak of aspergillosis in a flock of adult ostriches (Struthio camelus). Vet Rec 2003;153:124-125.
  13. Bezuidenhout AJ, Groenewald HB, Soley JT. An anatomical study of the respiratory air sacs in ostriches. Onderstepoort J Vet Res 1999;66:317-325.