Antibacterial effect of medicinal plants against Helicobacter pylori

헬리코박터 파이로리균에 대한 약용식물의 항균 효과

  • Received : 2018.12.27
  • Accepted : 2019.02.20
  • Published : 2019.02.28


The study was designed to investigate the antibacterial effect of Helicobacter pylori against 32 medicinal plants commonly used as health foods. The medicinal plants used in this study were 32 kinds of medicinal plant extracts using the disk diffusion method for H. pylori activity, which can be eaten every day by everyone. Amoxicillin sodium (150 mg / ml, Ildong Pharmaceutical) and Metronidazole 50 mg / ml) was used as a control group. We measured the area of the transparent area and evaluated that the larger the area, the more effective it is for H. pylori. As a result of this study, the clear zone of inhibition was highest at $372.90mm^2$, second was $358.30mm^2$, and Chungho was $348.32mm^2$. The positive control group, Metronidazole (50 mg / ml CJ), was $503,29mm^2$. In the future, the development of antimicrobial materials of various medicinal plants is expected to be effective for the inhibition of H. pylori.

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Fig. 1. Antibacterial effect of 32 medicinal plantsextracts as clear zone of inhibition (mm2)against H. pylori by paper disk diffusionmethods for 48h.

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Fig. 2. Antibacterial effect of 32 Antibiotics as clear zone of inhibition (mm2) against H. pylori by paper disk diffusion methods for 48h.

Table 1. Antibacterial effect of 32 medicinal plants extracts as clear zone of inhibition (mm2) against H. pylori by paper disk diffusion methods for 48h

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Table 2. Antibacterial effect of Antibiotics as clear zone of inhibition (mm2) against H. pylori by paper disk diffusion methods for 48h.

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Supported by : Nambu University


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