A Systematic Review of Herbal Medicine Treatment for Knee Osteoarthritis

퇴행성 슬관절염의 한약제제 치료에 대한 체계적 문헌고찰

  • Kim, Ji-Hoon (Department of Rehabilitation Medicine of Korean Medicine, College of Korean Medicine, Dongshin University) ;
  • Yoon, Young-Suk (Department of Rehabilitation Medicine of Korean Medicine, Jaseng Hospital of Korean Medicine) ;
  • Lee, Won-Jun (Department of Rehabilitation Medicine of Korean Medicine, Jaseng Hospital of Korean Medicine) ;
  • Ko, Hong-Je (Department of Acupuncture and Moxibustion, Dongshin University Mokpo Korean Medicine Hospital) ;
  • Kim, Seon-Jong (Department of Rehabilitation Medicine of Korean Medicine, College of Korean Medicine, Dongshin University)
  • 김지훈 (동신대학교 한의과대학 한방재활의학과교실) ;
  • 윤영석 (자생한방병원 한방재활의학과) ;
  • 이원준 (자생한방병원 한방재활의학과) ;
  • 고홍제 (동신대학교 목포한방병원 침구과) ;
  • 김선종 (동신대학교 한의과대학 한방재활의학과교실)
  • Received : 2019.09.11
  • Accepted : 2019.10.14
  • Published : 2019.10.31


Objectives This study reviewed recent clinical research trends regarding the effectiveness of herbal medicine treatments for knee osteoarthritis. Methods We reviewed 4 different online databases (PubMed, China National Knowledge Infrastructure [CNKI], National Digital Science Library [NDSL], Oriental Medicine Advanced Searching Integrated System [OASIS]) from January 1, 2015 to August 31, 2019. Results Thirty-two randomized controlled trial papers were selected in this review. Most of them were conducted during 12 weeks, used Western Ontario and Mcmaster Universities Arthritis Index. In 22 of the papers, the effectiveness in the intervention groups was significantly higher than that in the control groups statistically (p<0.05). 5 studies reported intervention group was not inferior to the control group. Conclusions Most of studies showed herbal medicine treatments were statistically effective to knee osteoarthritis. More scientific and systematic clinical studies should be actively conducted in the future, and the results of this study could be used as basic data in the future clinical studies on herbal medicine treatment for knee osteoarthritis.


Supported by : Dongshin University


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