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Safety and Efficacy of Low Level Laser for Alopecia : A Systematic Review

탈모에 대한 레이저의 안전성 및 유효성 : 체계적 문헌 고찰

  • Lee, Bo-Ram (Dept. of Beauty Design, Wonkwang University) ;
  • Lee, Ma-Eum (Dep. of Ophthalmology & Otolaryngology & Dermatology, Pusan National University Korean Medicine Hospital) ;
  • Ko, Kyoung-Sook (Dept. of Beauty Design, Wonkwang University) ;
  • Seo, Hyung-Sik (Dep. of Ophthalmology & Otolaryngology & Dermatology, Pusan National University Korean Medicine Hospital)
  • 이보람 (원광대학교 뷰티디자인학부) ;
  • 이마음 (부산대학교 한방병원 안이비인후피부과) ;
  • 고경숙 (원광대학교 뷰티디자인학부) ;
  • 서형식 (부산대학교 한방병원 안이비인후피부과)
  • Received : 2019.10.06
  • Accepted : 2019.10.25
  • Published : 2019.11.25

Abstract

Objectives : The purpose of this study is to determine the safety and efficacy of low level laser. Methods : We searched 11 electronic databases(Pubmed, CAJ, EMBASE, Medline, Cochrane Library, KMBASE, KISS, KISTI, NDSL, RISS, Oasis) up to March 2019. We included randomized controlled trials(RCTs) using low level laser for alopecia. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results : 8 RCT studies were eligible in our review. The meta-analysis of 2 studies showed favorable results for the use of low level laser with minoxidil 5% than minoxidil 5% and 6 studies showed favorable results for the use of low level laser than placebo light. The results of meta-analysis showed that low-level laser has an efficacy on alopecia. There were no serious side effects or adverse effects. High risk of bias were observed in all studies. Conclusion : Now limited evidence is available to support low level laser for alopecia and further well-designed RCTs should be encouraged.

Acknowledgement

Supported by : 부산대학교병원

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