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Review of Clinical Studies on the Treatment of Menopausal Depression Using Traditional Chinese Medicine -Focusing on Randomized Controlled Trial in CNKI

갱년기 우울증에 대한 중약 중재 임상연구 고찰 -CNKI에서 검색된 무작위배정 비교임상시험을 중심으로

  • Choi, Sung Ryul (Department of Oriental Neuropsychiatry, Jaseng Hospital of Korean Medicine) ;
  • Jung, Sung Yub (Department of Oriental Neuropsychiatry, Jaseng Hospital of Korean Medicine) ;
  • Hong, Doo Hyun (Department of Oriental Neuropsychiatry, Jaseng Hospital of Korean Medicine) ;
  • Yu, Jin Sil (Department of Oriental Obsterics and Gynecology, Jaseng Hospital of Korean Medicine) ;
  • Choi, Jong Ho (Department of Acupuncture and Moxibustion, Jaseng Hospital of Korean Medicine) ;
  • Kim, Mihye (Department of Korean Rehabilitation Medicine, Jaseng Hospital of Korean Medicine)
  • 최성률 (강남자생한방병원 한방신경정신과) ;
  • 정성엽 (강남자생한방병원 한방신경정신과) ;
  • 홍두현 (강남자생한방병원 한방신경정신과) ;
  • 유진실 (강남자생한방병원 한방부인과) ;
  • 최종호 (강남자생한방병원 침구의학과) ;
  • 김미혜 (강남자생한방병원 한방재활의학과)
  • Received : 2020.02.14
  • Accepted : 2020.03.16
  • Published : 2020.03.30

Abstract

Objectives: The objective of this study is to analyze clinical reports of treatment of menopausal depression in traditional Chinese medicine (TCM). Methods: This study included randomized controlled trials (RCT) in treating menopausal depression. Literature studies of Chinese National Knowledge Infrastructure Database(CNKI) were performed. Clinical reports on menopausal depression treatment were searched using the following key words in the CNKI: 'menopausal depression' and 'postmenopausal depression'. Results and Conclusions: A total of 24 RCT articles on menopausal depression were selected. The most widely used diagnostic tool for menopausal depression was CCMD-3. Effective rate and HAMD were the most commonly used assessment tools. Bosinhaeultang-gagam (Bushenjieyu-tang jiajian) and Gami-gammaegdaejotang(Jiawei ganmaidazao-tang) were used much more than other prescriptions, while Bupleuri Radix was the most used single medicine herb. Additionally, the Chinese medicine treatment group showed less adverse reactions than the control group. As a result, we could know frequently used herbal prescription and single medicinal herbs and this can be helpful in developing more advanced studies in future.

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