DOI QR코드

DOI QR Code

A Study on 3 Cases of Atopic Dermatitis in Children with Molluscum Contagiosum, Verruca Vulgaris

전염성 연속종과 보통 사마귀가 동반된 소아 아토피 피부염 3례 보고

  • Jo, Su-Ji (Pusan National University School of Korean Medicine) ;
  • Kim, Chul-Yun (Saengki Korean Medicine Clinic Pusan Seomyeon Branch) ;
  • Ha, U-Ram (Saengki Korean Medicine Clinic Pusan Centum Branch) ;
  • Kwon, Kang (Dep. of Korean Medicine Ophthalmology & Otolaryngology & Dermatology, Pusan National University School of Korean Medicine)
  • 조수지 (부산대학교 한의학전문대학원) ;
  • 김철윤 (생기한의원 부산 서면점) ;
  • 하우람 (생기한의원 부산 센텀점) ;
  • 권강 (부산대학교 한의학전문대학원 안이비인후피부과)
  • Received : 2020.04.03
  • Accepted : 2020.05.13
  • Published : 2020.05.25

Abstract

Objectives : Atopic dermatitis is a chronic inflammatory disease characterized by severe pruritus, and may be accompanied by Molluscum Contagiosum, Verruca Vulgaris. This paper aims to examine the clinical implications of the treatment of 3 cases of atopic dermatitis with Molluscum Contagiosum, Verruca Vulgaris. Methods : 3 patients were treated by herbal medicine, herbal acupuncture, acupuncture, moxibustion and external preparations. Photographs of lesions, VAS were used to evaluate the changes in symptoms. Results : Atopic dermatitis is accompanied by Molluscum Contagiosum or Verruca Vulgaris because the underlying cell layer is easily exposed to Molluscum Contagiosum and Human papilloma virus because of scatch by pruritus. And all three cases have been well recovered by korean medical treatment. Conclusions : This study shows that Korean medical treatment is effective to treat atopic dermatitis with Molluscum Contagiosum, Verruca Vulgaris.

References

  1. Shaw TE, Currie GP, Koudelka CW, Simpson EL. Eczema prevalence in the United States: data from the 2003 National Survey of Children's Health. Journal of Investigative Dermatology. 2011;131(1):67-73. https://doi.org/10.1038/jid.2010.251
  2. Drucker AM. Atopic dermatitis: burden of illness, quality of life, and associated complications. Allergy & Asthma Proceedings. 2017;38(1):3-8.
  3. Boguniewicz M, Fonacier L, Guttman-Yassky E, Ong PY, Silverberg J, Farrar JR. Atopic dermatitis yardstick: Practical recommendations for an evolving therapeutic landscape. Annals of Allergy, Asthma & Immunology. 2018;120(1):10-22. https://doi.org/10.1016/j.anai.2017.10.039
  4. Silverberg JI. Healthcare utilization, patient costs, and access to care in US adults with eczema: a population-based study. JAMA Dermatology. 2015;151(7):743-52. https://doi.org/10.1001/jamadermatol.2014.5432
  5. Leung DY. Atopic dermatitis and the immune system : The role of superantigens and bacteria. Journal of the American Academy of Dermatology. 2001;45(1 Suppl):13S-6S. https://doi.org/10.1067/mjd.2001.117024
  6. Cerio R. Therapy of atopic dermatitis. The journal of The European Academy of Dermatology and Venereology. 1997;8(1 Suppl):6S-10S. https://doi.org/10.1111/j.1468-3083.1997.tb01068.x
  7. Lee JH, Lee YW, Seo YJ, Ahn JY, Park YL, Son SW, et al. Treatment of Atopic Dermatitis. Korean Journal of Dermatology. 2018;56(10):581-93.
  8. Lee JB, Jo JH, Kim BS, Oh CG, Jang HS, Kwon KS, et al. 1 case of Molluscum Contagiosum with atopic dermatitis improved by antibiotic treatment. Programbook. 2003;55(1):101.
  9. Eichenfield LF, Tom WL, Chamlin SL, Feldman SR, Hanifin JM, Simpson EL, et al. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. Journal of the American Academy of Dermatology. 2014;70(2):338-51. https://doi.org/10.1016/j.jaad.2013.10.010
  10. Cho JE, Jeon YH, Yang HJ, Pyun BY. A study of the frequency and characteristics of minor clinical manifestations in children with atopic dermatitis. Korean Journal of Pediatrics. 2009;52(7):818-23. https://doi.org/10.3345/kjp.2009.52.7.818
  11. Lee HS, Kim JS, Pyun BY. Changes of the prevalence and the allergens of atopic dermatitis in children : in between the year of 1992 and 2002. Pediatric Allergy and Respiratory Disease(Korea). 2002;12(4):263-70.
  12. Imokawa G, Abe A, Jin KM, Migaki Y, Kqwashima M, Hidano A. Decreased levels of ceramides in stratum corneum of atopic dermatitis : an etiologic factor in atopic dry Skin. Journal of Investigative Dermatology. 1991;96(4):523-6. https://doi.org/10.1111/1523-1747.ep12470233
  13. Murata Y, Ogata J, Higaki Y, Kawashima M, Yada Y, Higuchi K, et al. Abnormal expression sphingomyelin acylase in atopic dermatitis : an etiologic factor for ceramide deficiency. Journal of Investigative Dermatology. 1996;106(6):1242-9. https://doi.org/10.1111/1523-1747.ep12348937
  14. Leung DY. Atopic dermatitis and the immune system : The role of superantigens and bacteria. Journal of the American Academy of Dermatology. 2001;45(1 Suppl):13S-6S. https://doi.org/10.1067/mjd.2001.117024
  15. Amatsu A, Yoshida M. Detection of Herpes simplex virus DNA in non-herpetic areas of pationts with eczema herpeticum. Dermatology. 2000;200(2):104-7. https://doi.org/10.1159/000018339
  16. Committee of Korean Dermatological Association. Textbook of Dermatology. 6th ed. Seoul:Daehan. 2015:461-2, 472-4.
  17. Schiller JT, Day PM, Kines RC. Current understanding of the mechanism of HPV infection. Gynecol Oncol. 2010;118(1 Suppl):S12-7. https://doi.org/10.1016/j.ygyno.2010.04.004
  18. Won JH, Nam IH, Lee SH, Ahn SK, Kim JG. Verruca vulgaris developed on the skin tag. Annals of Dermatology. 1994;6(1):105-7. https://doi.org/10.5021/ad.1994.6.1.105
  19. Kim SM, Ha KS, Ha SY, Kim HY, Song IS, Park SK, et al. Three Cases Report of Molluscum Contagiosum Children treated by Gwakhyangjeonggisangamibang. The Journal of Pediatrics of Korean Medicine. 2006;20(3):11-22.
  20. Jung Minyoung, Kim Minjung, Song Jinsu, Lee Yujin, Kim Jonghan, Park Sooyeon, Choi Jeonghwa. A case of eczema herpeticum with atopic dermatitis treated by Oriental Medicine. J Korean Med Ophthalmol Otolaryngol Dermatol. 2009;22(2):290-7.
  21. Coloe J, Morrell DS. Cantharidin use among pediatric dermatologists in the treatment of molluscum contagiosum. Pediatric Dermatology. 2009;26(4):405-8. https://doi.org/10.1111/j.1525-1470.2008.00860.x
  22. Syed TA, Lundin S, Ahmad M. Topical 0.3% and 0.5% podophyllotoxin cream for self-treatment of molluscum contagiosum in males. A placebo-controlled, double-blind study. Dermatology. 1994;189(1):65-8.
  23. Silverberg NB, Sidbury R, Mancini AJ. Childhood molluscum contagiosum: experience with cantharidin therapy in 300 patients. Journal of the American Academy of Dermatology. 2000;43(3):503-7. https://doi.org/10.1067/mjd.2000.106370
  24. Korean Traditional Dermatology Association Textbook Complication Committee. Text of Traditional Korean Dermatology & Surgery. 6th. Busan:Sunwoo. 2007:81-2,355-61.
  25. Jeong YH, Yoo DY. Experimental Study on the Immunoregulative Action of Kamiboatang. Journal of Korean Oriental Medicine. 2000;14(2):61-84.
  26. Son MJ, Lee SM, Park SH, Kim YG, Jung JY. The Effects of Orally Administrated Gwakhyangjeonggi-san on DNCB-induced Atopic Dermatitis like Mice Model. J Korean Med Ophthalmol Otolaryngol Dermatol. 2019;32(2):94-106.
  27. Jeong GM. A Study on the Effect of Bo A Tang Modified the Prescription of Sib Jeon Dae Bo Tang on the Body Weight of Growing Rat. The Journal of The Yellow-Emperor's Medicine. 1979;4(1):13-9.
  28. Im JG, Hong MC, Ha YM. The effect of Boa-tang to the lymphocytes. Journal of Oriental Physiology. 1999;14(02):83-97.
  29. Lee JH, Shim GS. Five Cases of Viral Warts Treated by Korean Medicine. J Korean Med Ophthalmol Otolaryngol Dermatol. 2015;28(2):121-9. https://doi.org/10.6114/jkood.2015.28.2.121
  30. Heo JH, Song HN, Jang SIl. Effects of Gagambojungikgi-tang on the Immune Mediators Regulation and Wound Healing in the rSj26 or Chemical Antigen induced Atopic Dermatitis Model Mice. The Korea Journal of Herbology. 2008;23(1):53-61.
  31. Korean Acupuncture & Moxibustion Society Textbook Compilation Committee. The Acupuncture and Moxibustion. 1st. Gyeonggi:Jipmoondang. 2012:822, 874.
  32. Korean Pharmacopuncture Institute Science Committee. Pharmacopucture. 2nd ed. Seoul:Elsvier Korea. 2008:3-8, 163-80, 259-420.